<3-(p-hydroxyphenyl)propionyl>-L-prolyl-N-methyl-D-leucine methyl ester

Base Information

• Chemical Name: <3-(p-hydroxyphenyl)propionyl>-L-prolyl-N-methyl-D-leucine methyl ester
• CAS No.: 130406-09-6
• Molecular Formula: C₂₂H₃₂N₂O₅
• Molecular Weight: 404.506
• Mol file: 130406-09-6.mol

Synonyms:<3-(p-hydroxyphenyl)propionyl>-L-prolyl-N-methyl-D-leucine methyl ester

Chemical Property of <3-(p-hydroxyphenyl)propionyl>-L-prolyl-N-methyl-D-leucine methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of <3-(p-hydroxyphenyl)propionyl>-L-prolyl-N-methyl-D-leucine methyl ester

There total 1 articles about <3-(p-hydroxyphenyl)propionyl>-L-prolyl-N-methyl-D-leucine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

4-hydroxyphenylpropionic acid (501-97-3) + L-prolyl-N-methyl-D-leucine methyl ester trifluoroacetate (117710-33-5) → <3-(p-hydroxyphenyl)propionyl>-L-prolyl-N-methyl-D-leucine methyl ester (130406-09-6)

Guidance literature:

With sodium hydrogencarbonate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In N,N-dimethyl-formamide; for 24h; Ambient temperature;

DOI:10.1021/jm00106a002

Reference yield: 85.0%

<3-(p-hydroxyphenyl)propionyl>-L-prolyl-N-methyl-D-leucine methyl ester (130406-09-6) → <3-(p-hydroxyphenyl)propionyl>-L-prolyl-N-methyl-D-leucine (130406-12-1)

Guidance literature:

With sodium hydroxide; In methanol; for 2h; Ambient temperature;

DOI:10.1021/jm00106a002

upstream raw materials:

4-hydroxyphenylpropionic acid

L-prolyl-N-methyl-D-leucine methyl ester trifluoroacetate

Downstream raw materials:

<3-(p-hydroxyphenyl)propionyl>-L-prolyl-N-methyl-D-leucine