3-benzyl-6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine

Base Information

• Chemical Name: 3-benzyl-6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine
• CAS No.: 1372853-92-3
• Molecular Formula: C₂₀H₁₄Cl₂N₂
• Molecular Weight: 353.251
• Mol file: 1372853-92-3.mol

Synonyms:3-benzyl-6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine

Chemical Property of 3-benzyl-6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-benzyl-6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine

There total 3 articles about 3-benzyl-6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

5-chloro-2-pyridylamine (1072-98-6) + 4-chlorobenzaldehyde (104-88-1) + phenylacetylene (536-74-3) → 3-benzyl-6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine (1372853-92-3)

Guidance literature:

With CuO nanoparticles onto reduced graphene oxide sheets; In dimethyl sulfoxide; at 110 ℃; Catalytic behavior;

DOI:10.1016/j.apcata.2017.05.033

Reference yield:

C12H10Cl2N2 + phenylacetylene (536-74-3) → 3-benzyl-6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine (1372853-92-3)

Guidance literature:

With copper(ll) sulfate pentahydrate; D-glucose; In ethanol; at 100 ℃;

DOI:10.1021/jo3003024

Reference yield:

5-chloro-2-pyridylamine (1072-98-6) + 4-chlorobenzaldehyde (104-88-1) → 3-benzyl-6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine (1372853-92-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.25 h

2: copper(ll) sulfate pentahydrate; D-glucose / ethanol / 100 °C

With copper(ll) sulfate pentahydrate; D-glucose; In ethanol;

DOI:10.1021/jo3003024

upstream raw materials:

5-chloro-2-pyridylamine

4-chlorobenzaldehyde

phenylacetylene