4-O-acetyl-3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinose diethyl dithioacetal

Base Information

• Chemical Name: 4-O-acetyl-3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinose diethyl dithioacetal
• CAS No.: 93215-36-2
• Molecular Formula: C₁₉H₃₀O₃S₂
• Molecular Weight: 370.577
• Mol file: 93215-36-2.mol

Synonyms:4-O-acetyl-3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinose diethyl dithioacetal

Chemical Property of 4-O-acetyl-3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinose diethyl dithioacetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-O-acetyl-3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinose diethyl dithioacetal

There total 2 articles about 4-O-acetyl-3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinose diethyl dithioacetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

acetic anhydride (108-24-7) + 3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinofuranose diethyl dithioacetal (93215-34-0) → 4-O-acetyl-3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinose diethyl dithioacetal (93215-36-2)

Guidance literature:

With pyridine; at 18 ℃;

DOI:10.1016/0008-6215(84)85225-8

Reference yield:

3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinofuranose (93215-31-7,93215-32-8) → 4-O-acetyl-3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinose diethyl dithioacetal (93215-36-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 20 percent / trifluoromethanesulfonic acid / 1.) 10 min, 0 deg C, 2.) 3 h, 20 deg C

2: 97 percent / pyridine / 18 °C

With pyridine; trifluorormethanesulfonic acid;

DOI:10.1016/0008-6215(84)85225-8

Reference yield: 92.0%

methanol (67-56-1) + 4-O-acetyl-3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinose diethyl dithioacetal (93215-36-2) → 4-O-acetyl-3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinose dimethyl acetal (93215-37-3)

Guidance literature:

With cadmium(II) carbonate; mercury dichloride; for 12h; Heating;

DOI:10.1016/0008-6215(84)85225-8

upstream raw materials:

acetic anhydride

3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinofuranose diethyl dithioacetal

3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinofuranose

Downstream raw materials:

4-O-acetyl-3-O-benzyl-2,5-dideoxy-2-C-methyl-D-arabinose dimethyl acetal