4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol

Base Information

• Chemical Name: 4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol
• CAS No.: 1221183-91-0
• Molecular Formula: C₁₃H₁₇NO₅S
• Molecular Weight: 299.348
• Mol file: 1221183-91-0.mol

Synonyms:4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol

Chemical Property of 4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol

There total 1 articles about 4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

1-oxa-6-thiaspiro<2.5>octane (185-73-9) + potassium 2-methoxy-4-nitrophenolate monohydrate (100200-99-5) → 4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol (1221183-91-0)

Guidance literature:

With sodium dihydrogenphosphate; In water; acetonitrile; at 150 ℃; for 3.5h; Microwave irradiation;

Reference yield: 91.0%

4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol (1221183-91-0) → 1,1-dioxido-4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol (1221183-92-1)

Guidance literature:

4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol; With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 20 ℃;

With sodium hydrogencarbonate; In N,N-dimethyl-formamide;

upstream raw materials:

1-oxa-6-thiaspiro<2.5>octane

potassium 2-methoxy-4-nitrophenolate monohydrate

Downstream raw materials:

1,1-dioxido-4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol