(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol

Base Information

Chemical Name:(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol
CAS No.:121933-59-3
Molecular Formula:C8H9NOS
Molecular Weight:167.232
Hs Code.:
DSSTox Substance ID:DTXSID10424359
Wikidata:Q82236897
Mol file:121933-59-3.mol

Synonyms:121933-59-3;(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol;(4-methylthieno[3,2-b]pyrrol-5-yl)methanol;{4-methyl-4H-thieno[3,2-b]pyrrol-5-yl}methanol;4H-Thieno[3,2-b]pyrrole-5-methanol, 4-methyl-;(4-Methyl-4H-thieno[3,2-b]pyrrol-5-yl)-methanol;SCHEMBL5036773;DTXSID10424359;MFCD07772838;AKOS006282099;AT18498;MS-22329;4-methyl-4h-thieno[3,2-b]pyrrol-5-ylmethanol;W-205131;(4-Methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol,97%;(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol, AldrichCPR

Suppliers and Price of (4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4-Methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol
100mg
$ 90.00

TRC
(4-Methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol
50mg
$ 60.00

American Custom Chemicals Corporation
(4-METHYL-4H-THIENO[3,2-B]PYRROL-5-YL)METHANOL 95.00%
1G
$ 756.76

American Custom Chemicals Corporation
(4-METHYL-4H-THIENO[3,2-B]PYRROL-5-YL)METHANOL 95.00%
250MG
$ 622.15

Total 6 raw suppliers

Chemical Property of (4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol

Chemical Property:

Melting Point:103 °C
Boiling Point:344.8 °C at 760 mmHg
Flash Point:162.3 °C
PSA：53.40000
Density:1.32 g/cm³
LogP:1.73210
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:167.04048508
Heavy Atom Count:11
Complexity:153

Purity/Quality:

97% ^*data from raw suppliers

(4-Methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C=C1CO)SC=C2

Technology Process of (4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol

There total 3 articles about (4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 106200-65-1
ethyl-4‐methyl‐4H‐thieno[3,2‐b]pyrro‐5‐carboxylate

: 121933-59-3
(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 0.75h; Inert atmosphere;
DOI:10.1021/acsmedchemlett.9b00604

Reference yield: 63.0%

: 857284-01-6
methyl 4-methyl-4H-thieno[3,2-b]pyrrole-5-carboxylate

: 121933-59-3
(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; Inert atmosphere;
DOI:10.1016/j.mencom.2018.03.028

Reference yield:

: 82782-85-2
thieno<3,2-b>pyrrole-5-carboxylic acid methyl ester

: 121933-59-3
(4-methyl-4H-thieno[3,2-b]pyrrol-5-yl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran / 0.5 h / Inert atmosphere

1.2: 40 °C / Inert atmosphere

2.1: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere

With lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran;
DOI:10.1016/j.mencom.2018.03.028