2-Pyrrolidinone,5-ethoxy-1-[1-(hydroxymethyl)-2-methylpropyl]-,[R-(R,S)]-(9CI)

Base Information

Chemical Name:2-Pyrrolidinone,5-ethoxy-1-[1-(hydroxymethyl)-2-methylpropyl]-,[R-(R*,S*)]-(9CI)
CAS No.:122383-41-9
Molecular Formula:C₁₁H₂₁NO₃
Molecular Weight:215.293
Hs Code.:
Mol file:122383-41-9.mol

Synonyms:2-Pyrrolidinone,5-ethoxy-1-[1-(hydroxymethyl)-2-methylpropyl]-,[R-(R*,S*)]-(9CI)

Suppliers and Price of 2-Pyrrolidinone,5-ethoxy-1-[1-(hydroxymethyl)-2-methylpropyl]-,[R-(R*,S*)]-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-Pyrrolidinone,5-ethoxy-1-[1-(hydroxymethyl)-2-methylpropyl]-,[R-(R*,S*)]-(9CI)

Chemical Property:

PSA：49.77000
LogP:0.92620

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Pyrrolidinone,5-ethoxy-1-[1-(hydroxymethyl)-2-methylpropyl]-,[R-(R*,S*)]-(9CI)

There total 2 articles about 2-Pyrrolidinone,5-ethoxy-1-[1-(hydroxymethyl)-2-methylpropyl]-,[R-(R*,S*)]-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4276-09-9,473-75-6
(R)-2-amino-3-methylbutanol

: 122383-38-4,122383-41-9
5-Ethoxy-1-((S)-1-hydroxymethyl-2-methyl-propyl)-pyrrolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / 3 h / 220 °C

2: NaBH₄, 2 M HCl / 3 h / Ambient temperature; pH 1-3

With hydrogenchloride; sodium tetrahydroborate;
DOI:10.1021/jo00278a053

Reference yield:

: 64-17-5
ethanol

: 122383-30-6
(S)-(+)-N-<1-(1-methylethyl)-2-hydroxyethyl>succinimide

: 122383-35-1
(3S,7aR)-3-Isopropyl-5-oxo-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole

: 122383-38-4,122383-41-9
5-Ethoxy-1-((S)-1-hydroxymethyl-2-methyl-propyl)-pyrrolidin-2-one

Guidance literature:: With hydrogenchloride; sodium tetrahydroborate; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature; pH 1-3;
DOI:10.1021/jo00278a053