(3S)-3-Phenylpentanal

Base Information

• Chemical Name: (3S)-3-Phenylpentanal
• CAS No.: 27855-02-3
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.232
• Mol file: 27855-02-3.mol

Synonyms:(3S)-3-Phenylpentanal

Chemical Property of (3S)-3-Phenylpentanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3S)-3-Phenylpentanal

There total 29 articles about (3S)-3-Phenylpentanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

carbon monoxide (201230-82-2) + 1-ethylstyrene (2039-93-2) → (3S)-3-Phenylpentanal (27855-02-3)

Guidance literature:

With (acetylacetonato)dicarbonylrhodium (l); (S,S)-YanPhos; hydrogen; In toluene; at 80 ℃; for 48h; under 3750.38 Torr; enantioselective reaction; Autoclave;

DOI:10.1021/jacs.8b00275

Reference yield: 89.0%

C13H16O2 → (3S)-3-Phenylpentanal (27855-02-3)

Guidance literature:

With water; potassium carbonate; In methanol; at 20 ℃; for 1h; optical yield given as %ee; Inert atmosphere;

DOI:10.1021/ja105585y

Reference yield: 74.0%

3-phenylpent-2-enal (32338-28-6) → (3S)-3-Phenylpentanal (27855-02-3)

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; (R)-(-)-2-(tert-butyl)-3-methyl-4-imidazolidinone trifluoroacetic acid salt; In chloroform; at -30 ℃; for 16h; Product distribution / selectivity;

upstream raw materials:

ethylmagnesium chloride

(4R)-2-((E)-2-Phenylethenyl)-4-phenyl-1,3-oxazolidine

(S)-(-)-1-Cinnamyl-(2-methoxymethyl)pyrrolidin

ethyl iodide

Downstream raw materials:

(+)-(S)-3-phenylpentan-1-ol

(3S)-3-Phenylpentyl-acetat