Technology Process of 2-tert-Butyl-3,3-dimethyl-4-phenyl-1-butanol
There total 5 articles about 2-tert-Butyl-3,3-dimethyl-4-phenyl-1-butanol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) NaNH2 / 1.) PhMe, r.t. to reflux, 150 min, 2.) PhMe, 2 h, reflux
3: 85 percent / SOCl2 / pyridine; petroleum ether / 24 h / 22 °C
4: 1.) NaBH4, BF3.OEt2, 2.) 3 M NaOH, 30percent H2O2 / 1.) O(C2H4OMe)2, 16 h, 22 deg C, 2.) 2 h, 22 deg C
With
sodium hydroxide; sodium tetrahydroborate; thionyl chloride; boron trifluoride diethyl etherate; dihydrogen peroxide; sodium amide;
In
pyridine; Petroleum ether;
- Guidance literature:
-
Multi-step reaction with 3 steps
2: 85 percent / SOCl2 / pyridine; petroleum ether / 24 h / 22 °C
3: 1.) NaBH4, BF3.OEt2, 2.) 3 M NaOH, 30percent H2O2 / 1.) O(C2H4OMe)2, 16 h, 22 deg C, 2.) 2 h, 22 deg C
With
sodium hydroxide; sodium tetrahydroborate; thionyl chloride; boron trifluoride diethyl etherate; dihydrogen peroxide;
In
pyridine; Petroleum ether;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 52 percent / CuCl / diethyl ether / 1.) 1 h, 0 deg C, 2.) 3 h, 22 deg C
2: 1.) NaNH2 / 1.) PhMe, r.t. to reflux, 150 min, 2.) PhMe, 2 h, reflux
4: 85 percent / SOCl2 / pyridine; petroleum ether / 24 h / 22 °C
5: 1.) NaBH4, BF3.OEt2, 2.) 3 M NaOH, 30percent H2O2 / 1.) O(C2H4OMe)2, 16 h, 22 deg C, 2.) 2 h, 22 deg C
With
sodium hydroxide; sodium tetrahydroborate; thionyl chloride; boron trifluoride diethyl etherate; dihydrogen peroxide; sodium amide; copper(l) chloride;
In
pyridine; diethyl ether; Petroleum ether;
