1(R*)-(dimethoxymethyl)-2(S*)-(phenylthio)-4(S*)-<(2,4-dinitrophenyl)amino>-1,2,3,4-tetrahydronaphthalene

Base Information

• Chemical Name: 1(R*)-(dimethoxymethyl)-2(S*)-(phenylthio)-4(S*)-<(2,4-dinitrophenyl)amino>-1,2,3,4-tetrahydronaphthalene
• CAS No.: 118629-79-1
• Molecular Formula: C₂₅H₂₅N₃O₆S
• Molecular Weight: 495.556
• Mol file: 118629-79-1.mol

Synonyms:1(R*)-(dimethoxymethyl)-2(S*)-(phenylthio)-4(S*)-<(2,4-dinitrophenyl)amino>-1,2,3,4-tetrahydronaphthalene

Chemical Property of 1(R*)-(dimethoxymethyl)-2(S*)-(phenylthio)-4(S*)-<(2,4-dinitrophenyl)amino>-1,2,3,4-tetrahydronaphthalene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 1(R*)-(dimethoxymethyl)-2(S*)-(phenylthio)-4(S*)-<(2,4-dinitrophenyl)amino>-1,2,3,4-tetrahydronaphthalene

There total 2 articles about 1(R*)-(dimethoxymethyl)-2(S*)-(phenylthio)-4(S*)-<(2,4-dinitrophenyl)amino>-1,2,3,4-tetrahydronaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-(2,4-dinitrophenyl)-3(R*)-methoxy-9(S*)-(phenylthio)-1(S*),4(R*)-ethano-1,2,3,4-tetrahydronaphthalene (118629-88-2) → 1(R*)-(dimethoxymethyl)-2(S*)-(phenylthio)-4(S*)-<(2,4-dinitrophenyl)amino>-1,2,3,4-tetrahydronaphthalene (118629-79-1)

Guidance literature:

With Dowex-50x8-400; In methanol; for 24h; Ambient temperature;

DOI:10.1021/jo00266a019

Reference yield:

2-(2,4-dinitrophenyl)-isoquinolinium chloride (33107-14-1) → 1(R*)-(dimethoxymethyl)-2(S*)-(phenylthio)-4(S*)-<(2,4-dinitrophenyl)amino>-1,2,3,4-tetrahydronaphthalene (118629-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / CaCO₃ / methanol / 72 h / 25 - 40 °C

2: 91 percent / Dowex-50X₈-400 / methanol / 24 h / Ambient temperature

With Dowex-50x8-400; calcium carbonate; In methanol;

DOI:10.1021/jo00266a019

Reference yield: 85.0%

1(R*)-(dimethoxymethyl)-2(S*)-(phenylthio)-4(S*)-<(2,4-dinitrophenyl)amino>-1,2,3,4-tetrahydronaphthalene (118629-79-1) → 1(R*)-(dimethoxymethyl)-2(S*)-(phenylthio)-4(S*)-amino-1,2,3,4-tetrahydronaphthalene (118629-84-8)

Guidance literature:

With Amberlite-IRA-400-OH^-; In water; acetone; for 48h; Ambient temperature;

DOI:10.1021/jo00266a019

upstream raw materials:

2-(2,4-dinitrophenyl)-3(R*)-methoxy-9(S*)-(phenylthio)-1(S*),4(R*)-ethano-1,2,3,4-tetrahydronaphthalene

2-(2,4-dinitrophenyl)-isoquinolinium chloride

Downstream raw materials:

1(R*)-(dimethoxymethyl)-2(S*)-(phenylthio)-4(S*)-amino-1,2,3,4-tetrahydronaphthalene