33107-14-1Relevant articles and documents
Structural verification of a tetrahydrotetrazole compound
Breton, Gary W.,Hahn, Lauren A.,Martin, Kenneth L.
, p. 1208 - 1212 (2019/09/18)
Tetrahydrotetrazoles are five-membered-ring heterocycles containing four contiguous saturated nitrogen atoms. Very few examples of such compounds have been reported in the literature. Our previous attempt at the synthesis of a member of this class of compound suggested that the N - N bonds may be more labile than expected. This finding raised the question as to whether the structures of any of the previously reported tetrahydrotetrazoles had been properly assigned. We have reproduced the synthesis of a reported tetrahydrotetrazole, namely 1,2-di-tert-butyl 3-phenyl-1H,2H,3H,10bH-[1,2,3,4]tetrazolo[5,1-a]isoquinoline-1,2-dicarboxylate, C25H30N4O4, and have now confidently confirmed its structure via X-ray crystallography. However, while sufficiently stable in the crystal phase, we discovered that it remains very labile in solution (having a half-life of only 15min at 20°C in CDCl3). A tentative reaction pathway for its dissociation based on 1H NMR spectral evidence is provided.
Isoquinolin-1-ylidenes as electronically tuneable ligands
Gomez-Bujedo, Silvia,Alcarazo, Manuel,Pichon, Christophe,Alvarez, Eleuterio,Fernandez, Rosario,Lassaletta, Jose M.
, p. 1180 - 1182 (2008/02/02)
The novel isoquinolin-1-ylidene ligands, introduced into Rh(i) complexes by exploiting the carbene-like reactivity of adducts 6, exhibit ligand properties similar to those of classic NHCs, and their electronic properties can be tuned by the introduction o
New chiral isoquinolinium salt derivatives from chiral primary amines via zincke reaction
Barbier, Denis,Marazano, Christian,Das, Bhupesh C.,Potier, Pierre
, p. 9596 - 9598 (2007/10/03)
-