C₄₄H₇₁N₁₃O₁₁

Base Information

• Chemical Name: C₄₄H₇₁N₁₃O₁₁
• CAS No.: 1276543-69-1
• Molecular Formula: C₄₄H₇₁N₁₃O₁₁
• Molecular Weight: 958.128
• Mol file: 1276543-69-1.mol

Synonyms:C₄₄H₇₁N₁₃O₁₁

Chemical Property of C₄₄H₇₁N₁₃O₁₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₄H₇₁N₁₃O₁₁

There total 5 articles about C₄₄H₇₁N₁₃O₁₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.3]heptadecane· (1276543-43-1) + [(2S,5R,8S,11S)-8-(4-Amino-butyl)-11-(3-guanidino-propyl)-5-(4-hydroxy-benzyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid (217099-14-4) → C44H71N13O11 (1276543-69-1)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; In water; at 4 ℃; for 10h; pH=8.5;

Reference yield:

1,8-bis-(benzyloxycarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane (1264659-72-4) → C44H71N13O11 (1276543-69-1)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium carbonate / toluene / 144 h / Reflux

2: hydrogen / palladium 10% on activated carbon / ethanol / 12 h / 20 °C

3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide / water / 10 h / 4 °C / pH 8.5

With hydrogen; sodium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; palladium 10% on activated carbon; In ethanol; water; toluene;

Reference yield:

4,11-bis-(benzyloxycarbonylmethyl)-1,4,8,11-tetraazabicyclo[6.6.3]heptadecane (1276543-46-4) → C44H71N13O11 (1276543-69-1)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen / palladium 10% on activated carbon / ethanol / 12 h / 20 °C

2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide / water / 10 h / 4 °C / pH 8.5

With hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide; palladium 10% on activated carbon; In ethanol; water;

upstream raw materials:

4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.3]heptadecane·

[(2S,5R,8S,11S)-8-(4-Amino-butyl)-11-(3-guanidino-propyl)-5-(4-hydroxy-benzyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaaza-cyclopentadec-2-yl]-acetic acid

1,4,8,11-tetraazatricyclo[9.3.1.14,8]hexadecane

1,8-bis-(benzyloxycarbonylmethyl)-1,4,8,11-tetraazacyclotetradecane