N-(3-chlorophenyl)-3,4,5-trimethoxybenzamide

Base Information

• Chemical Name: N-(3-chlorophenyl)-3,4,5-trimethoxybenzamide
• CAS No.: 6745-48-8
• Molecular Formula: C₁₆H₁₆ClNO₄
• Molecular Weight: 321.76
• European Community (EC) Number: 661-304-2
• Mol file: 6745-48-8.mol

Synonyms:N-(3-chlorophenyl)-3,4,5-trimethoxybenzamide;Oprea1_059383;AKOS002265564;AO-548/40085415

Chemical Property of N-(3-chlorophenyl)-3,4,5-trimethoxybenzamide

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 321.0767857
• Heavy Atom Count: 22
• Complexity: 354

Purity/Quality:

N-(3-CHLOROPHENYL)-3,4,5-TRIMETHOXYBENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C(=O)NC2=CC(=CC=C2)Cl

Technology Process of N-(3-chlorophenyl)-3,4,5-trimethoxybenzamide

There total 1 articles about N-(3-chlorophenyl)-3,4,5-trimethoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-aniline (108-42-9) + Eudesmic acid (118-41-2) → (3-Chlor-phenyl)-(3.4.5-trimethoxy-benzoyl)- (6745-48-8)

Guidance literature:

Eudesmic acid; With triphenylphosphine; In tetrachloromethane; acetonitrile; at 0 ℃; for 2h;

3-chloro-aniline; With triethylamine; In tetrachloromethane; acetonitrile; at 20 ℃;

Reference yield:

(3-Chlor-phenyl)-(3.4.5-trimethoxy-benzoyl)- (6745-48-8) → N-(3-chlorophenyl)-3,4,5-trihydroxybenzamide (330664-33-0)

Guidance literature:

With boron tribromide; In dichloromethane; at 30 ℃; for 3h;

upstream raw materials:

3-chloro-aniline

Eudesmic acid

Downstream raw materials:

N-(3-chlorophenyl)-3,4,5-trihydroxybenzamide