2-Chloro-1-(1H-indol-6-YL)ethanone

Base Information

Chemical Name:2-Chloro-1-(1H-indol-6-YL)ethanone
CAS No.:123216-45-5
Molecular Formula:C₁₀H₈ClNO
Molecular Weight:193.633
Hs Code.:2933998090
DSSTox Substance ID:DTXSID60558299
Nikkaji Number:J1.492.752B
Wikidata:Q82440544
Mol file:123216-45-5.mol

Synonyms:123216-45-5;2-CHLORO-1-(1H-INDOL-6-YL)ETHANONE;2-Chloro-1-(1H-indol-6-yl)ethan-1-one;Ethanone, 2-chloro-1-(1H-indol-6-yl)- (9CI);2-Chloro-1-(6-indolyl)ethanone;6-chloroacetylindole;Ethanone, 2-chloro-1-(1H-indol-6-yl)-;DTXSID60558299;MFCD13172818;SY278554;CS-0359129;F18274

Suppliers and Price of 2-Chloro-1-(1H-indol-6-YL)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-1-(1H-indol-6-yl)ethanone
5mg
$ 65.00

Apolloscientific
6-(Chloroacetyl)-1H-indole
250mg
$ 609.00

AccelPharmtech
2-chloro-1-(1H-indol-6-yl)-Ethanone 97.00%
25G
$ 4750.00

AccelPharmtech
2-chloro-1-(1H-indol-6-yl)-Ethanone 97.00%
1G
$ 1950.00

Total 5 raw suppliers

Chemical Property of 2-Chloro-1-(1H-indol-6-YL)ethanone

Chemical Property:

Melting Point:128-129 °C(Solv: ethanol (64-17-5))
Boiling Point:379.1±17.0 °C(Predicted)
PKA:15.56±0.30(Predicted)
PSA：32.86000
Density:1.337±0.06 g/cm3(Predicted)
LogP:2.58940
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:193.0294416
Heavy Atom Count:13
Complexity:207

Purity/Quality:

95+% ^*data from raw suppliers

2-Chloro-1-(1H-indol-6-yl)ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC2=C1C=CN2)C(=O)CCl

Technology Process of 2-Chloro-1-(1H-indol-6-YL)ethanone

There total 2 articles about 2-Chloro-1-(1H-indol-6-YL)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 92013-04-2
1-Acetyl-6-chloroacetylindole

: 123216-45-5
6-Chloroacetylindole

Guidance literature:: With sodium hydroxide; In methanol; water;
DOI:10.1016/S0040-4039(00)02313-3

Reference yield:

: 576-15-8
N-acetylindole

: 123216-45-5
6-Chloroacetylindole

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / AlCl₃ / CH₂Cl₂ / 20 °C

2: 96 percent / NaOH / methanol; H₂O

With sodium hydroxide; aluminium trichloride; In methanol; dichloromethane; water; 1: Friedel-Crafts acylation;
DOI:10.1016/S0040-4039(00)02313-3