1-Boc-2-trimethylsilanylpiperidine

Base Information

Chemical Name:1-Boc-2-trimethylsilanylpiperidine
CAS No.:123387-54-2
Molecular Formula:C₁₃H₂₇NO₂Si
Molecular Weight:257.448
Hs Code.:
DSSTox Substance ID:DTXSID80454380
Mol file:123387-54-2.mol

Synonyms:123387-54-2;1-BOC-2-TRIMETHYLSILANYLPIPERIDINE;Tert-butyl 2-trimethylsilylpiperidine-1-carboxylate;tert-butyl 2-(trimethylsilyl)piperidine-1-carboxylate;1-Piperidinecarboxylic acid, 2-(trimethylsilyl)-, 1,1-dimethylethyl ester;DTXSID80454380;AKOS015911803;1-BOC-2-TRIMETHYLSILYLPIPERIDINE;FT-0659368;A805064;tert-butyl2-(trimethylsilyl)piperidine-1-carboxylate

Suppliers and Price of 1-Boc-2-trimethylsilanylpiperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-BOC-2-TRIMETHYLSILANYLPIPERIDINE 95.00%
5G
$ 909.56

Total 6 raw suppliers

Chemical Property of 1-Boc-2-trimethylsilanylpiperidine

Chemical Property:

PSA：29.54000
LogP:4.01120
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:257.181105638
Heavy Atom Count:17
Complexity:278

Purity/Quality:

97% ^*data from raw suppliers

1-BOC-2-TRIMETHYLSILANYLPIPERIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCCCC1[Si](C)(C)C

Technology Process of 1-Boc-2-trimethylsilanylpiperidine

There total 9 articles about 1-Boc-2-trimethylsilanylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 75-77-4
chloro-trimethyl-silane

: 75844-69-8
t-butyl piperidinecarboxylate

: 123387-54-2
N-Boc-2-trimethylsilylpiperidine

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; at -78 ℃;
DOI:10.1016/S0040-4020(02)00322-8

Reference yield: 88.0%

: 75-77-4
chloro-trimethyl-silane

: 123387-55-3,1000075-49-9,1078727-67-9
1-t-butoxycarbonyl-2-tributylstannylpiperidine

: 123387-54-2
N-Boc-2-trimethylsilylpiperidine

Guidance literature:: 1-t-butoxycarbonyl-2-tributylstannylpiperidine; With n-butyllithium; 1,1'-(1R,2R)-cyclohexane-1,2-diyldipyrrolidine; In diethyl ether; at -10 ℃; for 0.166667h;

chloro-trimethyl-silane; at -78 - -10 ℃; Further stages.;
DOI:10.1039/b710066c

Reference yield:

: 1070-19-5
N-(tert-butyloxycarbonyl) azide

: 123387-54-2
N-Boc-2-trimethylsilylpiperidine

Guidance literature:: Multi-step reaction with 2 steps

1: dioxane

2: 88 percent / TMEDA; s-BuLi / -78 °C

With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In 1,4-dioxane;
DOI:10.1016/S0040-4020(02)00322-8