C₃₇H₃₈Cl₃NO₈

Base Information

• Chemical Name: C₃₇H₃₈Cl₃NO₈
• CAS No.: 1401413-71-5
• Molecular Formula: C₃₇H₃₈Cl₃NO₈
• Molecular Weight: 731.07
• Mol file: 1401413-71-5.mol

Synonyms:C₃₇H₃₈Cl₃NO₈

Chemical Property of C₃₇H₃₈Cl₃NO₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₇H₃₈Cl₃NO₈

There total 11 articles about C₃₇H₃₈Cl₃NO₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C34H37NO6 + 2,2,2-Trichloroethyl chloroformate (17341-93-4) → C37H38Cl3NO8 (1401413-71-5)

Guidance literature:

With sodium hydrogencarbonate; In tetrahydrofuran; at 20 ℃; for 4h; Inert atmosphere;

Reference yield:

D-glucosamine hydrochloride (14131-63-6) → C37H38Cl3NO8 (1401413-71-5)

Guidance literature:

Multi-step reaction with 12 steps

1.1: sodium hydrogencarbonate / water / 0.5 h / 20 °C

1.2: 4.5 h / 20 °C

2.1: pyridine / 0 - 20 °C

3.1: boron trifluoride diethyl etherate / dichloromethane / 0 - 20 °C

4.1: zinc; acetic acid / dichloromethane; methanol / 1 h / 0 - 20 °C / Inert atmosphere

5.1: sodium methylate / dichloromethane; methanol / 2 h / 20 °C

5.2: pH ~ 7

6.1: potassium carbonate; triflic azide / zinc(II) chloride / dichloromethane; water; methanol / 20 °C

7.1: camphorsulfonic acid / toluene / 2 h / 20 °C

8.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 - 20 °C

9.1: trifluorormethanesulfonic acid; triethylsilane / dichloromethane / 1 h / -78 °C

10.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C

10.2: 2 h / 20 °C

11.1: sodium hydroxide; trimethylphosphane / water; tetrahydrofuran / 20 °C

12.1: sodium hydrogencarbonate / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

With pyridine; triethylsilane; trifluorormethanesulfonic acid; triflic azide; boron trifluoride diethyl etherate; sodium methylate; sodium hydride; sodium hydrogencarbonate; potassium carbonate; acetic acid; sodium hydroxide; zinc; trimethylphosphane; zinc(II) chloride; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; mineral oil;

Reference yield:

1,3,4,6-tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranose (122210-05-3) → C37H38Cl3NO8 (1401413-71-5)

Guidance literature:

Multi-step reaction with 10 steps

1.1: boron trifluoride diethyl etherate / dichloromethane / 0 - 20 °C

2.1: zinc; acetic acid / dichloromethane; methanol / 1 h / 0 - 20 °C / Inert atmosphere

3.1: sodium methylate / dichloromethane; methanol / 2 h / 20 °C

3.2: pH ~ 7

4.1: potassium carbonate; triflic azide / zinc(II) chloride / dichloromethane; water; methanol / 20 °C

5.1: camphorsulfonic acid / toluene / 2 h / 20 °C

6.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 - 20 °C

7.1: trifluorormethanesulfonic acid; triethylsilane / dichloromethane / 1 h / -78 °C

8.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C

8.2: 2 h / 20 °C

9.1: sodium hydroxide; trimethylphosphane / water; tetrahydrofuran / 20 °C

10.1: sodium hydrogencarbonate / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

With triethylsilane; trifluorormethanesulfonic acid; triflic azide; boron trifluoride diethyl etherate; sodium methylate; sodium hydride; sodium hydrogencarbonate; potassium carbonate; acetic acid; sodium hydroxide; zinc; trimethylphosphane; zinc(II) chloride; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; mineral oil;

upstream raw materials:

2,2,2-Trichloroethyl chloroformate

D-glucosamine hydrochloride

1,3,4,6-tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranose

C₂₇H₂₉N₃O₆