ethyl 3-anilinohexanoate

Base Information

• Chemical Name: ethyl 3-anilinohexanoate
• CAS No.: 81942-11-2
• Molecular Formula: C₁₄H₂₁NO₂
• Molecular Weight: 235.326
• Mol file: 81942-11-2.mol

Synonyms:ethyl 3-anilinohexanoate

Chemical Property of ethyl 3-anilinohexanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 3-anilinohexanoate

There total 5 articles about ethyl 3-anilinohexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(Z)-3-Phenylamino-hex-2-enoic acid ethyl ester (158261-87-1) → ethyl 3-anilinohexanoate (81942-11-2)

Guidance literature:

With sodium tris(acetoxy)borohydride; In acetic acid; for 2h; Ambient temperature;

DOI:10.1021/jo00097a039

Reference yield:

ethyl hex-3-enoate (2396-83-0) + aniline (62-53-3) → N-phenylhex-3-enamide (859189-41-6) + ethyl 3-anilinohexanoate (81942-11-2)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; methanesulfonic acid; carbon monoxide; potassium iodide; 1,2-bis[di(t-butyl)phosphinomethyl]benzene; In toluene; at 140 ℃; for 16h; under 37503.8 Torr; Inert atmosphere; Autoclave; Sealed tube;

DOI:10.1039/c4cy00158c

Reference yield:

ethyl hex-3-enoate (2396-83-0) + carbon monoxide (201230-82-2) + aniline (62-53-3) → 6-phenylcarbamoyl-hexanoic acid ethyl ester + N-phenylhex-3-enamide (859189-41-6) + ethyl 3-anilinohexanoate (81942-11-2)

Guidance literature:

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; methanesulfonic acid; β-naphthol; potassium iodide; 1,2-bis[di(t-butyl)phosphinomethyl]benzene; In toluene; at 115 ℃; for 64h; under 37503.8 Torr; Inert atmosphere; Autoclave; Sealed tube;

DOI:10.1039/c4cy00158c

upstream raw materials:

(Z)-3-Phenylamino-hex-2-enoic acid ethyl ester

N-butylideneaniline

ethyl bromoacetate

ethyl hex-3-enoate

Downstream raw materials:

1-phenyl-4-propylazetidine-2-one

3-isopropylidene-1-phenyl-4-propylazetidine-2-one

3-(1-methylvinyl)-1-phenyl-4-propylazetidin-2-one

Phenyl-[1-(4,5,6,7-tetrahydro-benzofuran-3-yl)-butyl]-amine