4-Methoxy-pyridine-2-carboxylic acid hydrochloride

Base Information

Chemical Name:4-Methoxy-pyridine-2-carboxylic acid hydrochloride
CAS No.:123811-74-5
Molecular Formula:C7H7 N O3 . Cl H
Molecular Weight:189.598
Hs Code.:2933399090
European Community (EC) Number:840-552-7
DSSTox Substance ID:DTXSID60527985
Mol file:123811-74-5.mol

Synonyms:123811-74-5;4-Methoxypicolinic acid hydrochloride;4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE;4-Methoxypicolinic acid, HCl;4-methoxypyridine-2-carboxylic acid;hydrochloride;4-methoxypyridine-2-carboxylic acid hydrochloride;4-Methoxypicolinic Acid HCl;SCHEMBL6640953;DTXSID60527985;AB21831;BS-19574;EN300-261738;A805153;PYRIMIDINE, 2-METHYL-4-(4-PIPERIDINYL)-;2-Pyridinecarboxylic acid, 4-methoxy-, hydrochloride (1:1);4-Methoxypyridine-2-carboxylic acid--hydrogen chloride (1/1)

Suppliers and Price of 4-Methoxy-pyridine-2-carboxylic acid hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Methoxypicolinicacidhydrochloride 95+%
100g
$ 658.00

American Custom Chemicals Corporation
4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE 95.00%
500MG
$ 758.84

AK Scientific
4-Methoxy-pyridine-2-carboxylicacidhydrochloride
5g
$ 262.00

AK Scientific
4-Methoxy-pyridine-2-carboxylicacidhydrochloride
250mg
$ 171.00

AHH
4-Methoxy-pyridine-2-carboxylicacidhydrochloride 98%
5g
$ 446.00

Total 13 raw suppliers

Chemical Property of 4-Methoxy-pyridine-2-carboxylic acid hydrochloride

Chemical Property:

Vapor Pressure:1.22E-05mmHg at 25°C
Melting Point:148-150 °C
Refractive Index: ">
Boiling Point:354.5°Cat760mmHg
Flash Point:168.2°C
PSA：59.42000
Density:g/cm³
LogP:1.59040
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:189.0192708
Heavy Atom Count:12
Complexity:149

Purity/Quality:

97% ^*data from raw suppliers

4-Methoxypicolinicacidhydrochloride 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=NC=C1)C(=O)O.Cl

Technology Process of 4-Methoxy-pyridine-2-carboxylic acid hydrochloride

There total 4 articles about 4-Methoxy-pyridine-2-carboxylic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 36057-44-0
2-cyano-4-methoxylpyridine

: 123811-74-5
2-carboxy-4-methoxypyridin-1-ium chloride

Guidance literature:: With hydrogenchloride; In water; at 100 ℃;
DOI:10.1002/chem.202000117

Reference yield:

: 1122-96-9
4-methoxypyridine N-oxide

: 123811-74-5
2-carboxy-4-methoxypyridin-1-ium chloride

Guidance literature:: Multi-step reaction with 2 steps

1: dimethylcarbamyl chloride / CH₂Cl₂ / 24 h / Ambient temperature

2: 71 percent / 6 N HCl / 24 h / Heating

With hydrogenchloride; N,N-Dimethylcarbamoyl chloride; In dichloromethane;
DOI:10.1021/jo00289a058

Reference yield:

: 620-08-6,1232006-56-2
4-methoxypyridine

: 123811-74-5
2-carboxy-4-methoxypyridin-1-ium chloride

Guidance literature:: Multi-step reaction with 3 steps

1: 30percent hydrogen peroxide / acetic acid / 24 h / Heating

2: dimethylcarbamyl chloride / CH₂Cl₂ / 24 h / Ambient temperature

3: 71 percent / 6 N HCl / 24 h / Heating

With hydrogenchloride; dihydrogen peroxide; N,N-Dimethylcarbamoyl chloride; In dichloromethane; acetic acid;
DOI:10.1021/jo00289a058