t-Butoxyformamid, N-methyl-N-[4-(1-pyrrolidinyl)-2-butynyl]-

Base Information

Chemical Name:t-Butoxyformamid, N-methyl-N-[4-(1-pyrrolidinyl)-2-butynyl]-
CAS No.:124045-68-7
Molecular Formula:C₁₄H₂₄N₂O₂
Molecular Weight:252.357
Hs Code.:
Mol file:124045-68-7.mol

Synonyms:t-Butoxyformamid, N-methyl-N-[4-(1-pyrrolidinyl)-2-butynyl]-

Suppliers and Price of t-Butoxyformamid, N-methyl-N-[4-(1-pyrrolidinyl)-2-butynyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of t-Butoxyformamid, N-methyl-N-[4-(1-pyrrolidinyl)-2-butynyl]-

Chemical Property:

PSA：32.78000
LogP:1.89040

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of t-Butoxyformamid, N-methyl-N-[4-(1-pyrrolidinyl)-2-butynyl]-

There total 2 articles about t-Butoxyformamid, N-methyl-N-[4-(1-pyrrolidinyl)-2-butynyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 124045-68-7
(tert-butyloxycarbonyl)-N-methyl-4-(1-pyrrolidinyl)-2-butynamine

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 1 h / 25 °C

2: CuCl / dioxane / 1.) 25 deg C, 4 h, 2.) 50 deg C, 1 h

With copper(l) chloride; In 1,4-dioxane; methanol;
DOI:10.1021/jm00164a044

Reference yield:

: 123-75-1
pyrrolidine

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 124045-51-8
N-t-butoxycarbonyl-N-methylpropargylamine

: 124045-68-7
(tert-butyloxycarbonyl)-N-methyl-4-(1-pyrrolidinyl)-2-butynamine

Guidance literature:: With copper(l) chloride; In 1,4-dioxane; 1.) 25 deg C, 4 h, 2.) 50 deg C, 1 h;
DOI:10.1021/jm00164a044

Reference yield:

: 124045-68-7
(tert-butyloxycarbonyl)-N-methyl-4-(1-pyrrolidinyl)-2-butynamine

: 124045-49-4
N-Methyl-N-[4-(1-pyrrolidinyl)-2-butynyl]-3-methoxycarbonylpropanamide

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic acid (TFA) / 0 °C

2: 65 percent / triethylamine (TEA) / acetonitrile / 2 h

3: 66 percent / Dowex 50W

With Dowex 50W; triethylamine; trifluoroacetic acid; In acetonitrile;
DOI:10.1021/jm00164a044