dibromo[1,1'-bis(diphenylphosphino)ferrocene]palladium(II)

Base Information

• Chemical Name: dibromo[1,1'-bis(diphenylphosphino)ferrocene]palladium(II)
• CAS No.: 124268-93-5
• Molecular Formula: C34H28 Br2 Fe P2 Pd
• Molecular Weight: 820.619
• Mol file: 124268-93-5.mol

Synonyms:Palladium,[1,1'-bis(diphenylphosphino)ferrocene-P,P']dibromo-, (SP-4-2)-; Ferrocene,1,1'-bis(diphenylphosphino)-, palladium complex

Chemical Property of dibromo[1,1'-bis(diphenylphosphino)ferrocene]palladium(II)

Chemical Property:

• Melting Point: 274-282°C
• PSA: 27.18000
• LogP: 8.08010

Purity/Quality:

99% ^*data from raw suppliers

Dibromo[1,1′-bis(diphenylphosphino)ferrocene]palladium(II) 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of dibromo[1,1'-bis(diphenylphosphino)ferrocene]palladium(II)

There total 4 articles about dibromo[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,1'-bis-(diphenylphosphino)ferrocene (12150-46-8) + (C7H8)PdBr2 (42765-77-5) → {1,1'-bis(diphenylphosphino)ferrocene} palladium dibromide (124268-93-5)

Guidance literature:

In acetone; to suspn. of Pd-complex in acetone Fe-complex was added, stirred at roomtemp. for 2 h under inert atm.; vol. was reduced in vac., Et2O was added, stirred for 10 min, filtered, washed with Et2O, dried under vac.;

DOI:10.1016/S0022-328X(01)00981-0

Reference yield:

1,1'-bis-(diphenylphosphino)ferrocene (12150-46-8) + tetrakis(triphenylphosphine) palladium(0) (14221-01-3) + 2-bromo-2,2-difluoro-1-morpholine-1-yl-ethanone (149229-27-6) → {1,1'-bis(diphenylphosphino)ferrocene} palladium dibromide (124268-93-5) + [(1,1-bis(diphenylphosphino)ferrocene)Pd(Br)(CF2CON(CH2CH2)2O)]

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; 2-bromo-2,2-difluoro-1-morpholine-1-yl-ethanone; In toluene; at 50 ℃; for 4.5h; Inert atmosphere; Sealed tube; Glovebox;

1,1'-bis-(diphenylphosphino)ferrocene; In toluene; at 20 ℃; for 16h; Overall yield = 83 %; Overall yield = 303 mg; Inert atmosphere;

DOI:10.1021/jacs.7b09949

Reference yield:

1,1'-bis-(diphenylphosphino)ferrocene (12150-46-8) + tetrakis(triphenylphosphine) palladium(0) (14221-01-3) + 2-bromo-2,2-difluoro-N,N-dimethyl-acetamide → {1,1'-bis(diphenylphosphino)ferrocene} palladium dibromide (124268-93-5) + [(1,1-bis(diphenylphosphino)ferrocene)Pd(Br)(CF2CONMe2)]

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; 2-bromo-2,2-difluoro-N,N-dimethyl-acetamide; In toluene; at 50 ℃; for 24h; Inert atmosphere; Sealed tube; Glovebox;

1,1'-bis-(diphenylphosphino)ferrocene; In toluene; at 20 ℃; for 3.5h; Overall yield = 94 %; Overall yield = 325 mg; Inert atmosphere;

DOI:10.1021/jacs.7b09949

upstream raw materials:

1,1'-bis-(diphenylphosphino)ferrocene

(C₇H₈)PdBr₂

tetrakis(triphenylphosphine) palladium⁽⁰⁾

2-bromo-N,Ν-diethyl-2,2-difluoroacetamide

Downstream raw materials:

[1,1'-bis(diphenylphosphino)ferrocene]Pd(η(2)-cyclooctatetraene)

(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride

[Pd(O₄C₂)(1,1'-bis(diphenylphosphino)ferrocene)]

[(1,10-bis(diphenylphosphino)ferrocene)Pd(trifluoroacetate)₂]

Refernces

• 1、 Colacot, Thomas J.,Qian, Hu,Cea-Olivares, Raymundo,Hernandez-Ortega, Simon. "Synthesis, X-ray, spectroscopic and a preliminary Suzuki coupling screening studies of a complete series of dppfMX2 (M=Pt, Pd; X=Cl, Br, I)". . p. 691 - 697. Retrieved 2007/10/03.