2-Fluoro-6-isopropylaniline

Base Information

Chemical Name:2-Fluoro-6-isopropylaniline
CAS No.:126476-48-0
Molecular Formula:C9H12 F N
Molecular Weight:153.199
Hs Code.:
DSSTox Substance ID:DTXSID80566972
Wikidata:Q82452748
Mol file:126476-48-0.mol

Synonyms:2-Fluoro-6-isopropylaniline;126476-48-0;2-fluoro-6-propan-2-ylaniline;2-Fluoro-6-(propan-2-yl)aniline;BENZENAMINE, 2-FLUORO-6-(1-METHYLETHYL)-;Benzenamine, 2-fluoro-6-(1-methylethyl)- (9CI);2-fluoro-6-isopropyl aniline;SCHEMBL9751353;DTXSID80566972;VZWWFQXGHKEDAN-UHFFFAOYSA-N;MFCD18824824;AKOS024050120;SB76010;AS-64564;CS-0343430;W13839;EN300-2956419

Suppliers and Price of 2-Fluoro-6-isopropylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 2-Fluoro-6-isopropylaniline

Chemical Property:

Boiling Point:207.1±20.0 °C(Predicted)
PKA:3.03±0.10(Predicted)
PSA：26.02000
Density:1.049±0.06 g/cm3(Predicted)
LogP:3.11250
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:153.095377549
Heavy Atom Count:11
Complexity:125

Purity/Quality:: 99%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=C(C(=CC=C1)F)N

Technology Process of 2-Fluoro-6-isopropylaniline

There total 4 articles about 2-Fluoro-6-isopropylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1449199-67-0
1-fluoro-2-nitro-3-(prop-1-en-2-yl)benzene

: 126476-48-0
2-fluoro-6-isopropylaniline

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In ethyl acetate; at 20 ℃; under 760.051 Torr; Inert atmosphere;

Reference yield: 77.0%

: 65896-11-9
2-bromo-6-fluoroaniline

: 77047-87-1
isopropyl zinc bromide

: 126476-48-0
2-fluoro-6-isopropylaniline

Guidance literature:: With palladium diacetate; In tetrahydrofuran; at 20 ℃; for 3h; Inert atmosphere; Sealed tube;

Reference yield:

: 886762-70-5
2?bromo?6?fluoronitrobenzene

: 126476-48-0
2-fluoro-6-isopropylaniline

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate; bis-triphenylphosphine-palladium(II) chloride / water; 1,4-dioxane / 80 °C / Inert atmosphere

2: hydrogen; 5%-palladium/activated carbon / ethyl acetate / 20 °C / 760.05 Torr / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; 5%-palladium/activated carbon; hydrogen; sodium carbonate; In 1,4-dioxane; water; ethyl acetate;