methyl 4H-thieno[3,2-c]chromene-2-carboxylate

Base Information

• Chemical Name: methyl 4H-thieno[3,2-c]chromene-2-carboxylate
• CAS No.: 126522-01-8
• Molecular Formula: C₁₃H₁₀O₃S
• Molecular Weight: 246.287
• DSSTox Substance ID: DTXSID70393931
• Wikidata: Q82192999
• ChEMBL ID: CHEMBL1352800
• Mol file: 126522-01-8.mol

Synonyms:126522-01-8;methyl 4H-thieno[3,2-c]chromene-2-carboxylate;Methyl 4H-[1]-benzopyrano[4,3-b]thiophene-2-carboxylate;4H-Thieno[3,2-c][1]benzopyran-2-carboxylic acid, methyl ester;UPCMLD-DP156;MLS000116102;ChemDiv3_007587;SCHEMBL987836;CHEMBL1352800;UPCMLD-DP156:001;DTXSID70393931;HMS1494I19;HMS2247G07;AKOS001489494;CCG-125129;IDI1_025497;SMR000093086;WS-02439;CS-0301989;D86520;J-005389;METHYL 4H-(1)-BENZOPYRANO(4 3-B)THIOPHE&;BRD-K79690564-001-01-5;Z17053279;methyl 3~{a},4-dihydro-3~{H}-thieno[3,2-c]chromene-2-carboxylate;Methyl 4H-[1]-benzopyrano[4,3-b]thiophene-2-carboxylate, 97%

Chemical Property of methyl 4H-thieno[3,2-c]chromene-2-carboxylate

Chemical Property:

• Vapor Pressure: 8.65E-08mmHg at 25°C
• Refractive Index: 1.629
• Boiling Point: 435.6°C at 760 mmHg
• Flash Point: 217.2°C
• PSA: 63.77000
• Density: 1.334g/cm³
• LogP: 3.09410
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 246.03506535
• Heavy Atom Count: 17
• Complexity: 307

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methyl 4H-[1]-benzopyrano[4,3-b]thiophene-2-carboxylate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1=CC2=C(S1)C3=CC=CC=C3OC2

Technology Process of methyl 4H-thieno[3,2-c]chromene-2-carboxylate

There total 3 articles about methyl 4H-thieno[3,2-c]chromene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methanol (67-56-1) + 4H-thieno[3,2-c]-chromene-2-carboxylic acid (26268-04-2) → methyl 4H-thieno[3,2-c]chromene-2-carboxylate (126522-01-8)

Guidance literature:

With thionyl chloride; for 2.5h; Reflux;

DOI:10.1007/s10593-015-1642-4

Reference yield:

thieno[3,2-c][1]benzopyran-2(4H)-carboxaldehyde → methyl 4H-thieno[3,2-c]chromene-2-carboxylate (126522-01-8)

Guidance literature:

Multi-step reaction with 2 steps

1: silver(l) oxide / tetrahydrofuran / 2 h / 10 °C

2: thionyl chloride / 2.5 h / Reflux

With thionyl chloride; silver(l) oxide; In tetrahydrofuran;

DOI:10.1007/s10593-015-1642-4

Reference yield:

→ methyl 4H-thieno[3,2-c]chromene-2-carboxylate (126522-01-8)

Guidance literature:

upstream raw materials:

methanol

4H-thieno[3,2-c]-chromene-2-carboxylic acid

Downstream raw materials:

4H-thieno[3,2-c]-chromene-2-carboxylic acid

C₁₉H₁₄ClNO₂S

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 126522-01-8 METHYL 4H-(1)-BENZOPYRANO(4 3-B)THIOPHE&

Send

Send

Metric Ton KG G Pound L ML

Send

Send