(S)-2-Chloro-1-(4-fluorophenyl)ethanol

Base Information

Chemical Name:(S)-2-Chloro-1-(4-fluorophenyl)ethanol
CAS No.:126534-42-7
Molecular Formula:C8H8 Cl F O
Molecular Weight:174.602
Hs Code.:2906299090
European Community (EC) Number:824-863-5
DSSTox Substance ID:DTXSID801254949
Nikkaji Number:J1.843.863A
Wikidata:Q76414958
Mol file:126534-42-7.mol

Synonyms:126534-42-7;(S)-2-CHLORO-1-(4-FLUOROPHENYL)ETHANOL;(1S)-2-chloro-1-(4-fluorophenyl)ethanol;(1S)-2-chloro-1-(4-fluorophenyl)ethan-1-ol;(S)-1-chloro-2-hydroxy-2-(p-fluorophenyl)ethane;SCHEMBL2298019;VTCREIYEGAGUDS-MRVPVSSYSA-N;Benzenemethanol, alpha-(chloromethyl)-4-fluoro-, (alphaS)-;DTXSID801254949;AKOS006284650;AS-68440;(S)-1-(4-Fluorophenyl)-2-chloroethanol;2-chloro-(1S)-1-(4-fluorophenyl)ethanol;CS-0062157;(S)-2-chloro-1-(4-fluorophenyl)ethan-1-ol;(s)-2-chloro-4'-fluoro-1-phenylethan-1-ol;EN300-182072;(alphaS)-alpha-(Chloromethyl)-4-fluorobenzenemethanol

Suppliers and Price of (S)-2-Chloro-1-(4-fluorophenyl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(1S)-2-chloro-1-(4-fluorophenyl)ethan-1-ol
100mg
$ 265.00

ChemScene
(S)-1-Chloro-2-hydroxy-2-(p-fluorophenyl)ethane
250mg
$ 289.00

ChemScene
(S)-1-Chloro-2-hydroxy-2-(p-fluorophenyl)ethane
1g
$ 741.00

ChemScene
(S)-1-Chloro-2-hydroxy-2-(p-fluorophenyl)ethane
100mg
$ 180.00

Apolloscientific
(S)-2-Chloro-1-(4-fluorophenyl)ethanol 98%
250mg
$ 174.00

Apolloscientific
(S)-2-Chloro-1-(4-fluorophenyl)ethanol 98%
1g
$ 522.00

American Custom Chemicals Corporation
(S)-2-CHLORO-1-(4-FLUOROPHENYL)ETHANOL 95.00%
5MG
$ 500.15

Ambeed
(S)-2-Chloro-1-(4-fluorophenyl)ethanol 98%
5g
$ 131.00

Ambeed
(S)-2-Chloro-1-(4-fluorophenyl)ethanol 98%
1g
$ 39.00

Ambeed
(S)-2-Chloro-1-(4-fluorophenyl)ethanol 98%
250mg
$ 15.00

Total 23 raw suppliers

Chemical Property of (S)-2-Chloro-1-(4-fluorophenyl)ethanol

Chemical Property:

Boiling Point:256.6±25.0 °C(Predicted)
PKA:13.14±0.20(Predicted)
PSA：20.23000
Density:1.282±0.06 g/cm3(Predicted)
LogP:2.09790
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:174.0247707
Heavy Atom Count:11
Complexity:113

Purity/Quality:

99%, ^*data from raw suppliers

(1S)-2-chloro-1-(4-fluorophenyl)ethan-1-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(CCl)O)F
Isomeric SMILES:C1=CC(=CC=C1[C@@H](CCl)O)F

Technology Process of (S)-2-Chloro-1-(4-fluorophenyl)ethanol

There total 12 articles about (S)-2-Chloro-1-(4-fluorophenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 456-04-2
2-Chloro-4'-fluoroacetophenone

: 126534-42-7,134356-70-0
(S)-1-chloro-2-hydroxy-2-(p-fluorophenyl)ethane

Guidance literature:: With bis(1,5-cyclooctadiene)diiridium(I) dichloride; f-amphox; hydrogen; potassium carbonate; In ethanol; hexane; at 25 - 30 ℃; for 4h; under 38002.6 Torr; enantioselective reaction; Inert atmosphere; Glovebox; Autoclave;
DOI:10.1002/adsc.201800267

Reference yield:

: 456-04-2
2-Chloro-4'-fluoroacetophenone

: 126534-42-7,134356-70-0
(S)-1-chloro-2-hydroxy-2-(p-fluorophenyl)ethane

: 126534-43-8,134356-70-0
[R]-1-chloro-2-(4-fluorophenyl)-2-ethanol

Guidance literature:: With benzo[1,3,2]dioxaborole; chiral boron-bis(oxazoline) derivative; In dichloromethane; at 25 ℃; for 48h;
DOI:10.1002/ejoc.200600133

Reference yield:

: (R,S)-2-chloro-1-(4-fluorophenyl)ethyl acetate

: 126534-42-7,134356-70-0
(S)-1-chloro-2-hydroxy-2-(p-fluorophenyl)ethane

: (R)-1-chloro-2-acetoxy-2-(p-fluorophenyl)ethane

Guidance literature:: With Candida antarctica lipase B; In aq. phosphate buffer; at 45 ℃; for 6h; pH=7; enantioselective reaction; Enzymatic reaction;
DOI:10.1016/j.mcat.2020.110819