2-Amino-4-methoxyl-7-(2,3-O-isopropylidene-5-O-tert-butyldimethylsilyl--D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine

Base Information

Chemical Name:2-Amino-4-methoxyl-7-(2,3-O-isopropylidene-5-O-tert-butyldimethylsilyl--D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine
CAS No.:131981-22-1
Molecular Formula:C21H34N4O5Si
Molecular Weight:450.6
Hs Code.:
Mol file:131981-22-1.mol

Synonyms:2-Amino-4-methoxyl-7-(2,3-O-isopropylidene-5-O-tert-butyldimethylsilyl--D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine;7-[5-O-[(1,1-Dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)- -D-ribofuranosyl]-4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine

Suppliers and Price of 2-Amino-4-methoxyl-7-(2,3-O-isopropylidene-5-O-tert-butyldimethylsilyl--D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-[5-O-[(1,1-Dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β-D-ribofuranosyl]-4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine
50mg
$ 1540.00

TRC
7-[5-O-[(1,1-Dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β-D-ribofuranosyl]-4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine
5mg
$ 195.00

Total 2 raw suppliers

Chemical Property of 2-Amino-4-methoxyl-7-(2,3-O-isopropylidene-5-O-tert-butyldimethylsilyl--D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine

Chemical Property:

Refractive Index:1.584
PSA：102.88000
LogP:4.04260
Solubility.:Dichloromethane, Methanol

Purity/Quality:

95% ^*data from raw suppliers

7-[5-O-[(1,1-Dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β-D-ribofuranosyl]-4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 7-[5-O-[(1,1-Dimethylethyl)dimethylsilyl]-2,3-O-(1-methylethylidene)-β -D-ribofuranosyl]-4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine (cas# 131981-22-1) is a compound useful in organic synthesis.

Technology Process of 2-Amino-4-methoxyl-7-(2,3-O-isopropylidene-5-O-tert-butyldimethylsilyl--D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine

There total 2 articles about 2-Amino-4-methoxyl-7-(2,3-O-isopropylidene-5-O-tert-butyldimethylsilyl--D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 124-41-4
sodium methylate

: 115479-40-8
4-chloro-7-{5′-O-[(1,1-dimethylethyl)-dimethylsilyl]-2′,3′-O-(1-methylethylidene)-β-D-ribofuranosyl}-7H-pyrrolo[2,3-d]pyrimidine-2-amine

: 131981-22-1
7-{5'-O-[(1,1-dimethylethyl)dimethylsilyl]-2',3'-O-(1-methylethylidene)-β-D-ribofuranosyl}-4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine

Guidance literature:: With methanol; at 70 ℃; for 4.5h;
DOI:10.1016/0960-894X(96)00459-3

Reference yield:

: 102690-94-8
2,3-O-isopropylidene-5-O-(tert-butyldimethylsilyl)-α-D-ribofuranosyl chloride

: 84955-32-8
2-amino-4-methoxy-7H-pyrrolo[2,3-d]-pyrimidine

: 131981-22-1
7-{5'-O-[(1,1-dimethylethyl)dimethylsilyl]-2',3'-O-(1-methylethylidene)-β-D-ribofuranosyl}-4-methoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amine

Guidance literature:: With potassium hydroxide; Tris(3,6-dioxaheptyl)amine; Yield given. Multistep reaction; 1) MeCN, 10 min, 2) r.t., 20 h;
DOI:10.1002/hlca.19900730710