2-Amino-4,5-dihydrothiophene-3-carboxamide

Base Information

Chemical Name:2-Amino-4,5-dihydrothiophene-3-carboxamide
CAS No.:133036-77-8
Molecular Formula:C5H8N2OS
Molecular Weight:144.19
Hs Code.:2934999090
DSSTox Substance ID:DTXSID70564821
Wikidata:Q82449655
Mol file:133036-77-8.mol

Synonyms:2-Amino-4,5-dihydrothiophene-3-carboxamide;133036-77-8;5-Amino-2,3-dihydrothiophene-4-carboxamide;3-Thiophenecarboxamide,2-amino-4,5-dihydro-(9CI);MFCD18819330;DTXSID70564821;AKOS006341794

Suppliers and Price of 2-Amino-4,5-dihydrothiophene-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Oakwood
2-Amino-4,5-dihydrothiophene-3-carboxamide
5g
$ 3570.00

Crysdot
2-Amino-4,5-dihydrothiophene-3-carboxamide 95+%
5g
$ 3365.00

Arctom
2-Amino-4,5-dihydrothiophene-3-carboxamide 95%
1g
$ 1120.00

Total 2 raw suppliers

Chemical Property of 2-Amino-4,5-dihydrothiophene-3-carboxamide

Chemical Property:

Melting Point:138-139 °C(Solv: acetone (67-64-1))
Boiling Point:370.3±42.0 °C(Predicted)
PKA:15.47±0.20(Predicted)
PSA：94.41000
Density:1.393±0.06 g/cm3(Predicted)
LogP:1.17950
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:144.03573406
Heavy Atom Count:9
Complexity:176

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

2-Amino-4,5-dihydrothiophene-3-carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CSC(=C1C(=O)N)N

Technology Process of 2-Amino-4,5-dihydrothiophene-3-carboxamide

There total 2 articles about 2-Amino-4,5-dihydrothiophene-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 133036-76-7
tetrahydro-2-oxo-3-thiophenecarbonitrile

: 133036-77-8
2-amino-4,5-dihydrothiophene-3-carboxamide

Guidance literature:: With ammonium hydroxide; for 1h; Heating;

Reference yield:

: 52989-46-5
2-amino-4,5-dihydro-3-thiophenecarbonitrile

: 133036-77-8
2-amino-4,5-dihydrothiophene-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / 5percent aq. HCl / 0.5 h / 60 °C

2: 81 percent / conc. NH₄OH / 1 h / Heating

With hydrogenchloride; ammonium hydroxide;