Propanoic acid, 2-methyl-, methyl ester, radical ion(1-) (9CI)

Base Information

• Chemical Name: Propanoic acid, 2-methyl-, methyl ester, radical ion(1-) (9CI)
• CAS No.: 133320-07-7
• Molecular Formula: C5H10O2
• Molecular Weight: 102.13
• Mol file: 133320-07-7.mol

Synonyms:

Chemical Property of Propanoic acid, 2-methyl-, methyl ester, radical ion(1-) (9CI)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Propanoic acid, 2-methyl-, methyl ester, radical ion(1-) (9CI)

There total 112 articles about Propanoic acid, 2-methyl-, methyl ester, radical ion(1-) (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl 2-dimethylbismuthanyl-2-methylpropanoate (934733-52-5) → Methyl isobutyrate (547-63-7,133320-07-7,67505-84-4)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene-d6; at 80 ℃; for 1h;

DOI:10.1002/anie.200604473

Reference yield: 96.0%

methanol (67-56-1) + prednisolone 21-isobutyrate → prednisolon (50-24-8,8056-11-9) + Methyl isobutyrate (547-63-7,133320-07-7,67505-84-4)

Guidance literature:

With triethylamine; at 20 ℃; for 2h; under 8250660 Torr; Product distribution;

DOI:10.1002/hlca.200490135

Reference yield: 95.0%

O-methyl selenoisobutirate (76047-09-1) → Methyl isobutyrate (547-63-7,133320-07-7,67505-84-4)

Guidance literature:

With oxygen; methyl iodide; triethylphosphine; In benzene; at 50 ℃; for 5h;

upstream raw materials:

diazomethane

isobutyryl bromide

methanol

2-methyl-propan-1-ol

Downstream raw materials:

acrylic acid methyl ester

4-isopropyl-2,6-dimethyl-heptan-4-ol

1-cyclohexyl-2,2-dimethyl-1-propanone

2-Methyloctane-3,4-dione

Refernces

• 1、 Terashima, Takaya,Ouchi, Makoto,Ando, Tsuyoshi,Sawamoto, Mitsuo. "In situ hydrogenation of terminal halogen in poly(methyl methacrylate) by ruthenium-catalyzed living radical polymerization: Direct transformation of "polymerization catalyst" into "hydrogenation catalyst"". . p. 11014 - 11015. Retrieved 2006.
• 2、 Rasuwaew,Ol'dekop. "-". . p. 1173;engl.Ausg.S.1233. Retrieved 1953.
• 3、 Kollar, Laszlo,Consiglio, Giambattista,Pino, Piero. "ASYMMETRIC HYDROFORMYLATION OF UNSATURATED ESTERS WITH PtCl(SnCl3) CATALYST". . p. 305 - 314. Retrieved 1987.
• 4、 Roth, Jerome A.,Grega, Kevin,Orchin, Milton. "Stoichiometric hydrogenation of α,β-unsaturated ketones by HCo(CO)4". . p. 129 - 136. Retrieved 1988.
• 5、 Koeken, Ard C. J.,Smeets, Niels M. B.. "A bulky phosphite modified rhodium catalyst for efficient hydroformylation of disubstituted alkenes and macromonomers in supercritical carbon dioxide". . p. 1036 - 1045. Retrieved 2013.
• 6、 Jedlinski, Zbigniew,Janeczek, Henryk,Bosek, Izabela. "Methyl methacrylate. Unusual two-electron transfer reaction and carbanion generation". . p. 4956 - 4958. Retrieved 1999.
• 7、 Fry,A.J.,Migron,Y.. "-". . p. 3357 - 3360. Retrieved 1979.
• 8、 Chen, Jiawei,Chen, Eugene X.-Y.. "Reactivity of amine/E(C6 F5 )3 (E = B, Al) lewis pairs toward linear and cyclic acrylic monomers: Hydrogenation vs. polymerization". . p. 9575 - 9590. Retrieved 2015.
• 9、 Ribelli, Thomas G.,Rahaman, S. M. Wahidur,Matyjaszewski, Krzysztof,Poli, Rinaldo. "Catalyzed Radical Termination in the Presence of Tellanyl Radicals". . p. 13879 - 13882. Retrieved 2017.
• 10、 Beller, Matthias,Feng, Lu,Gao, Jie,Jackstell, Ralf,Jagadeesh, Rajenahally V.,Liu, Yuefeng,Ma, Rui. "Ambient Hydrogenation and Deuteration of Alkenes Using a Nanostructured Ni-Core–Shell Catalyst". supporting information. p. 18591 - 18598. Retrieved 2021/06/28.