5'-O-(4,4'-DIMETHOXYTRITYL)-O6-PHENYL-2'-DEOXYINOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE

Base Information

Chemical Name:5'-O-(4,4'-DIMETHOXYTRITYL)-O6-PHENYL-2'-DEOXYINOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE
CAS No.:133471-07-5
Molecular Formula:C46H51N6O7P
Molecular Weight:830.91
Hs Code.:
Mol file:133471-07-5.mol

Synonyms:O6-PHENYL-DL CEP;5'-O-(4,4'-DIMETHOXYTRITYL)-O6-PHENYL-2'-DEOXYINOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE

Suppliers and Price of 5'-O-(4,4'-DIMETHOXYTRITYL)-O6-PHENYL-2'-DEOXYINOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5'-O-(4,4'-DIMETHOXYTRITYL)-O-6-PHENYL-2'-DEOXYINOSINE-3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE 95.00%
5MG
$ 500.48

Total 2 raw suppliers

Chemical Property of 5'-O-(4,4'-DIMETHOXYTRITYL)-O6-PHENYL-2'-DEOXYINOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE

Chemical Property:

PSA：148.83000
LogP:9.59318

Purity/Quality:

95% ^*data from raw suppliers

5'-O-(4,4'-DIMETHOXYTRITYL)-O-6-PHENYL-2'-DEOXYINOSINE-3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5'-O-(4,4'-DIMETHOXYTRITYL)-O6-PHENYL-2'-DEOXYINOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE

There total 3 articles about 5'-O-(4,4'-DIMETHOXYTRITYL)-O6-PHENYL-2'-DEOXYINOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 37595-87-2
2-Cyanoethyl Phosphorodichloridate

: 7087-68-5
N-ethyl-N,N-diisopropylamine

: 133471-08-6
5'-O-(4,4'-dimethoxytrityl)-O⁶-phenyl-2'-deoxyinosine

: 133471-07-5
5'-O-(4,4'-dimethoxytrityl)-O⁶-phenyl-2'-deoxyinosine 3'-(2-cyanoethyl-N,N-diisopropyl) phosphoramidite

Guidance literature:: In dichloromethane; for 2h; Ambient temperature;
DOI:10.1021/ja00073a016

Reference yield:

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 133471-07-5
5'-O-(4,4'-dimethoxytrityl)-O⁶-phenyl-2'-deoxyinosine 3'-(2-cyanoethyl-N,N-diisopropyl) phosphoramidite

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / pyridine, 4-(dimethylamino)pyridine / 16 h / Ambient temperature

2: 96 percent / CH₂Cl₂ / 2 h / Ambient temperature

With pyridine; dmap; In dichloromethane;
DOI:10.1021/ja00073a016

Reference yield:

: 114485-36-8
6-(2-deoxy-β-D-erythro-pentofuranosyl)-6-phenoxypurine

: 133471-07-5
5'-O-(4,4'-dimethoxytrityl)-O⁶-phenyl-2'-deoxyinosine 3'-(2-cyanoethyl-N,N-diisopropyl) phosphoramidite

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / pyridine, 4-(dimethylamino)pyridine / 16 h / Ambient temperature

2: 96 percent / CH₂Cl₂ / 2 h / Ambient temperature

With pyridine; dmap; In dichloromethane;
DOI:10.1021/ja00073a016