BIOTIN AMIDITE

Base Information

Chemical Name:BIOTIN AMIDITE
CAS No.:135137-87-0
Molecular Formula:C46H64N5O6PS
Molecular Weight:846.084
Hs Code.:
Mol file:135137-87-0.mol

Synonyms:

Suppliers and Price of BIOTIN AMIDITE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
[1-N-(4,4’-Dimethoxytrityl)biotinyl-6-aminohexyl]-2-(cyanoethyl-N,N-diisopropyl)phosphoramidite
100mg
$ 1230.00

TRC
[1-N-(4,4’-Dimethoxytrityl)biotinyl-6-aminohexyl]-2-(cyanoethyl-N,N-diisopropyl)phosphoramidite
10mg
$ 155.00

Sigma-Aldrich
DMT-Biotin-C6 Phosphoramidite configured for PerkinElmer, configured for Polygen
0.1mmol
$ 209.00

Sigma-Aldrich
DMT-Biotin-C6 Phosphoramidite configured for ABI
0.1mmol
$ 209.00

Sigma-Aldrich
DMT-Biotin-C6 Phosphoramidite configured for ABI
0.25g
$ 618.00

Sigma-Aldrich
DMT-Biotin-C6 Phosphoramidite configured for PerkinElmer, configured for Polygen
0.25g
$ 618.00

Biosynth Carbosynth
5'-Biotin phosphoramidite
500 mg
$ 525.00

Biosynth Carbosynth
5'-Biotin phosphoramidite
250 mg
$ 300.00

Biosynth Carbosynth
5'-Biotin phosphoramidite
5 g
$ 2750.00

Biosynth Carbosynth
5'-Biotin phosphoramidite
2 g
$ 1350.00

Total 7 raw suppliers

Chemical Property of BIOTIN AMIDITE

Chemical Property:

Boiling Point:934.9±65.0 °C(Predicted)
PKA:13.16±0.40(Predicted)
PSA：164.28000
LogP:10.06070
Storage Temp.:-20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

[1-N-(4,4’-Dimethoxytrityl)biotinyl-6-aminohexyl]-2-(cyanoethyl-N,N-diisopropyl)phosphoramidite ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Reagent used in the preparation of Biotinylated oligonucleotides.

Technology Process of BIOTIN AMIDITE

There total 5 articles about BIOTIN AMIDITE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 135137-86-9
4,4'-dimethoxytrityl-biotinyl-6-aminohexanol

: 102691-36-1
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite

: 135137-87-0
C₄₆H₆₄N₅O₆PS

Guidance literature:: With 1H-tetrazole; In dichloromethane; at 20 ℃; for 0.25h; Inert atmosphere;
DOI:10.1016/j.bmc.2011.09.035

Reference yield:

: 135137-86-9
4,4'-dimethoxytrityl-biotinyl-6-aminohexanol

: 102690-88-0
bis(2-cyanoethyl) diisopropylamidophosphite

: 135137-87-0
C₄₆H₆₄N₅O₆PS

Guidance literature:: With 1H-tetrazole; In dichloromethane; at 20 ℃; for 1.5h; Inert atmosphere;
DOI:10.1039/b719938d

Reference yield:

: 58-85-5,22879-79-4
biotin

: 135137-87-0
C₄₆H₆₄N₅O₆PS

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 4 h / 80 °C

2: di(succinimido) carbonate / N,N-dimethyl-formamide / 1 h

3: trtrazolium / acetonitrile / 0.17 h

With pyridine; di(succinimido) carbonate; In N,N-dimethyl-formamide; acetonitrile;