Bromozinc(1+);1-chlorohexane

Base Information

• Chemical Name: Bromozinc(1+);1-chlorohexane
• CAS No.: 135579-83-8
• Molecular Formula: C6H12BrClZn
• Molecular Weight: 264.908
• DSSTox Substance ID: DTXSID70393835
• Mol file: 135579-83-8.mol

Synonyms:bromozinc(1+);1-chlorohexane;135579-83-8;6-CHLOROHEXYLZINC BROMIDE;DTXSID70393835;J-006722

Chemical Property of Bromozinc(1+);1-chlorohexane

Chemical Property:

• Vapor Pressure: 10.2mmHg at 25°C
• Refractive Index: ">
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 0.00000
• Density: g/cm³
• LogP: 3.59630
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 261.91023
• Heavy Atom Count: 9
• Complexity: 29.4

Purity/Quality:

98% ^*data from raw suppliers

6-Chlorohexylzincbromide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xn
• Statements: 14-19-22-36/38-40-36/37-11
• Safety Statements: 16-26-33-36-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: [CH2-]CCCCCCl.[Zn+]Br

Technology Process of Bromozinc(1+);1-chlorohexane

There total 2 articles about Bromozinc(1+);1-chlorohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromo-6-chlorohexane (6294-17-3) → 6-chlorohexylzinc bromide (135579-83-8)

Guidance literature:

With iodine; zinc; In N,N-dimethyl acetamide; at 60 ℃; for 5h; Inert atmosphere;

Reference yield:

1-bromo-6-chlorohexane (6294-17-3) + zinc (7440-66-6) → 6-chlorohexylzinc bromide (135579-83-8)

Guidance literature:

With iodine; In N,N-dimethyl acetamide; at 80 ℃; for 16h; Inert atmosphere;

DOI:10.1021/ol303129p

Reference yield: 89.0%

4-cyanophenyldiazonium tetrafluoroborate (2252-32-6) + 6-chlorohexylzinc bromide (135579-83-8) → 3-(4-chlorobutyl)-5-cyanoindole (143612-79-7)

Guidance literature:

With formic acid; In toluene; at -44 - 120 ℃; for 1.33333h; under 228.015 Torr; Temperature; Solvent; Reagent/catalyst; Inert atmosphere;

upstream raw materials:

1-bromo-6-chlorohexane

zinc

Downstream raw materials:

2-(1-(benzyloxy)-10-chlorodecan-2-yl)isoindoline-1,3-dione

N-(8-chloro-2-phenyloctyl)-4-methylbenzenesulfonamide

1-cyclohexylnonan-4-yl 1-naphthoate

3-(4-chlorobutyl)-5-cyanoindole

Refernces

• 1、 Huang, Chung-Yang,Doyle, Abigail G.. "Electron-deficient olefin ligands enable generation of quaternary carbons by Ni-catalyzed cross-coupling". supporting information. p. 5638 - 5641. Retrieved 2015/05/20.