2-(5-CHLORO-1H-BENZOIMIDAZOL-2-YL)-ETHYLAMINE

Base Information

• Chemical Name: 2-(5-CHLORO-1H-BENZOIMIDAZOL-2-YL)-ETHYLAMINE
• CAS No.: 135875-16-0
• Molecular Formula: C9H10ClN3
• Molecular Weight: 195.651
• Hs Code.: 2933990090
• Mol file: 135875-16-0.mol

Synonyms:AKOS B006823;2-(5-CHLORO-1H-BENZOIMIDAZOL-2-YL)-ETHYLAMINE;2-AMINOETHYL-5(6)-CHLORO-BENZIMIDAZOLE;ART-CHEM-BB B006823;CHEMBRDG-BB 4110558;TIMTEC-BB SBB009274;1H-Benzimidazole-2-ethanamine,5-chloro-(9CI)

Chemical Property of 2-(5-CHLORO-1H-BENZOIMIDAZOL-2-YL)-ETHYLAMINE

Chemical Property:

• Vapor Pressure: 1.14E-07mmHg at 25°C
• Refractive Index: 1.685
• Boiling Point: 432.1°C at 760 mmHg
• PKA: 11.41±0.10(Predicted)
• Flash Point: 215.1°C
• PSA: 54.70000
• Density: 1.363g/cm³
• LogP: 2.41780
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

97% ^*data from raw suppliers

2-(6-Chloro-1H-benzimidazol-2-yl)ethanamine hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 37/38-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(5-CHLORO-1H-BENZOIMIDAZOL-2-YL)-ETHYLAMINE

There total 3 articles about 2-(5-CHLORO-1H-BENZOIMIDAZOL-2-YL)-ETHYLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

4-Chloro-1,2-phenylenediamine (95-83-0) + 3-amino propanoic acid (107-95-9) → 2-(5-chloro-1H-1,3-benzodiazol-2-yl)ethan-1-amine (135875-16-0)

Guidance literature:

With hydrogenchloride; Heating;

Reference yield:

3-(5-chloro-1(3)H-benzimidazol-2-yl)-propionic acid amide (143949-75-1) → 2-(5-chloro-1H-1,3-benzodiazol-2-yl)ethan-1-amine (135875-16-0)

Guidance literature:

Reference yield:

→ 2-(5-chloro-1H-1,3-benzodiazol-2-yl)ethan-1-amine (135875-16-0)

Guidance literature:

4-Chlor-1,2-diaminobenzol, β-Alanin III, Δ, HClaq;

upstream raw materials:

3-(5-chloro-1⁽³⁾H-benzimidazol-2-yl)-propionic acid amide

4-Chloro-1,2-phenylenediamine

3-amino propanoic acid

Downstream raw materials:

4-N-[2-(5-chloro-1H-1,3-benzodiazol-2-yl)ethyl]-6-(2,3-dimethylphenyl)pyrimidine-2,4-diamine