D-Gulono-1,4-lactone 2,3,5,6-Tetraacetate

Base Information

• Chemical Name: D-Gulono-1,4-lactone 2,3,5,6-Tetraacetate
• CAS No.: 136345-68-1
• Molecular Formula: C₁₄H₁₈O₁₀
• Molecular Weight: 346.291
• Mol file: 136345-68-1.mol

Synonyms:(2S,3R,4R)-2-[(1R)-1,2-bis(acetyloxy)ethyl]-5-oxotetrahydrofuran-3,4-diyl diacetate (non-preferred name);

Chemical Property of D-Gulono-1,4-lactone 2,3,5,6-Tetraacetate

Chemical Property:

• Vapor Pressure: 4.45E-06mmHg at 25°C
• Melting Point: 88-93°C
• Refractive Index: 1.483
• Boiling Point: 383.3 °C at 760 mmHg
• Flash Point: 165.9 °C
• PSA: 131.50000
• Density: 1.33 g/cm³
• LogP: -0.73000
• Storage Temp.: Refrigerator
• Solubility.: Chloroform, Dichloromethane, Ethyl Acetate, Methanol

Purity/Quality:

99% ^*data from raw suppliers

D-Gulono-1,4-lactone 2,3,5,6-Tetraacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: D-Gulono-1,4-lactone derivative D-Gulono-1,4-lactone derivative.

Technology Process of D-Gulono-1,4-lactone 2,3,5,6-Tetraacetate

There total 6 articles about D-Gulono-1,4-lactone 2,3,5,6-Tetraacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

2,3,4,6-tetra-O-acetyl-1-bromo-1-deoxy-β-D-galactopyranosyl cyanide (83497-42-1) → 3,4,5,7-tetra-O-acetyl-2,6-anhydro-D-lyxo-hept-2-enononitrile (120085-67-8) + 2,3,5,6-tetra-O-acetyl-D-galactono-1,4-lactone (65143-68-2,69881-31-8,79580-58-8,79580-59-9,112241-17-5,136345-67-0,136345-68-1)

Guidance literature:

With mercury(II) cyanide; In dimethyl sulfoxide; at 100 ℃;

DOI:10.1016/0008-6215(91)84157-A

Reference yield:

acetic anhydride (108-24-7) + D-galactono-1,4-lactone (2782-07-2) → 2,3,5,6-tetra-O-acetyl-D-galactono-1,4-lactone (65143-68-2,69881-31-8,79580-58-8,79580-59-9,112241-17-5,136345-67-0,136345-68-1)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01303a052

Reference yield:

acetic anhydride (108-24-7) + D-gulono-1,4-lactone (6322-07-2) → tetra-O-acetyl-D-gulono-1,4-lactone (136345-68-1)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01303a052

upstream raw materials:

acetic anhydride

D-talonic acid γ-lactone

D-galactono-1,4-lactone

D-gulono-1,4-lactone

Downstream raw materials:

O²,O³,O⁵,O⁶-tetraacetyl-DL-galactonic acid-lactone

D-galactono-1,4-lactone