2782-07-2 Usage
Uses
D-Galactono-1,4-lactone was used in carbohydrate research as an elution compound for the purification process of exo-β-D-galactofuranosidase enzyme.
Definition
ChEBI: A galactonolactone derived from D-galactonic acid.
Purification Methods
Crystallise the lactone from EtOH, aqueous EtOH, MeOH or EtOAc. It is also purified by passage through a column of Amberlite IR-120 (H+ form), and the effluent and washings are then freeze-dried [Wolfrom & Thompson Methods in Carbohydrate Chemistry I 67 1963, Academic Press]. The 5,6-O-isopropylidene-D-galactono-1,4-lactone is purified by chromatography (EtOAc) and has m 165-167o (from EtOH/hexane), and 167.5-168.5o (from Me2CO/*C6H6) [NMR: Copel & Stick Aust J Chem 31 1371 1978.] [Beilstein 18 III/IV 3026, 18/5 V 18.]
Check Digit Verification of cas no
The CAS Registry Mumber 2782-07-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,8 and 2 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2782-07:
(6*2)+(5*7)+(4*8)+(3*2)+(2*0)+(1*7)=92
92 % 10 = 2
So 2782-07-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H10O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-5,7-10H,1H2/t2-,3-,4-,5+/m1/s1
2782-07-2Relevant articles and documents
Lien
, p. 1363,1364 (1959)
A simple synthesis of D-galactono-1,4-lactone and key building blocks for the preparation of galactofuranosides
De Talance, Vincent Lemau,Thiery, Emilie,Eppe, Guillaume,Bkassiny, Sandy El,Mortier, Jeremie,Vincent, Stephane P.
experimental part, p. 605 - 617 (2012/06/04)
The oxidation of D-galactose by Br2 to yield D-galactono-1,4-lactone was developed and applied to the preparation of key building blocks for the synthesis of galactofuranosides. Three D-galactono-1,4-lactone derivatives protected as acetates, TBDMS ether, or acetonide were directly obtained in two steps on multigram scale with only one purification step. A mild deacetylation methodology afforded pure D-galactono-1,4-lactone and a new reduction of the lactone functionality using K-selectride was also optimized.
A new efficient access to glycono-1,4-lactones by oxidation of unprotected itols by catalytic hydrogen transfer with RhH(PPh3)4-benzalacetone system
Isaac,Aizel,Stasik,Wadouachi,Beaupère
, p. 475 - 476 (2007/10/03)
Treatment of unprotected pentitols and hexitols with RhH(PPh3)4-benzalacetone system leads exclusively to glycono-1,4-lactones in 60-96% yield.
