D-galactono-1,4-lactone

Base Information

• Chemical Name: D-galactono-1,4-lactone
• CAS No.: 2782-07-2
• Molecular Formula: C6H10O6
• Molecular Weight: 178.142
• Hs Code.: 29322090
• European Community (EC) Number: 220-484-9
• DSSTox Substance ID: DTXSID40904659
• Nikkaji Number: J208.533J
• Wikidata: Q27098286
• Metabolomics Workbench ID: 50299
• ChEMBL ID: CHEMBL466882
• Mol file: 2782-07-2.mol

Synonyms:D-galactono-1,4-lactone;2782-07-2;gamma-D-galactonolactone;D-Galactonic acid 1,4-lactone;D-galactonic acid gamma-lactone;(3R,4R,5S)-5-((R)-1,2-Dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-one;1,4-D-Galactonolactone;galactono-gamma-lactone;CHEBI:15895;D-Galactonic acid, gamma-lactone;(3R,4R,5S)-5-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-one;D-galactono-gamma-lactone;D-galactonate-gamma-lactone;D-Galactonic 1,4-lactone;D-Galactono-I(3)-Iacton;D-galactonic acid g-lactone;Galactonic acid-1,4-lactone;SCHEMBL346605;CHEMBL466882;DTXSID40904659;EINECS 220-484-9;D-(-)-galactonic acid gamma-lactone;AKOS006271546;NSC 102762;CS-0450439;C03383;Q27098286;6E3F7E1D-5F52-4C31-AE17-BDEE150F1E24;WURCS=2.0/1,1,0/[A2112h_1-4]/1/

Chemical Property of D-galactono-1,4-lactone

Chemical Property:

• Vapor Pressure: 1.01E-10mmHg at 25°C
• Melting Point: 137 °C
• Refractive Index: 1.625
• Boiling Point: 467.9 °C at 760 mmHg
• PKA: 12.06±0.60(Predicted)
• Flash Point: 201.5 °C
• PSA: 107.22000
• Density: 1.766 g/cm³
• LogP: -3.01320
• XLogP3: -2
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 178.04773803
• Heavy Atom Count: 12
• Complexity: 181

Purity/Quality:

98%, ^*data from raw suppliers

D-Galactono-1,4-lactone ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C1C(C(C(=O)O1)O)O)O)O
• Isomeric SMILES: C([C@H]([C@H]1[C@@H]([C@H](C(=O)O1)O)O)O)O
• Uses: D-Galactono-1,4-lactone was used in carbohydrate research as an elution compound for the purification process of exo-β-D-galactofuranosidase enzyme.

Technology Process of D-galactono-1,4-lactone

There total 18 articles about D-galactono-1,4-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

D-Galactose (10257-28-0) → D-galactono-1,4-lactone (2782-07-2)

Guidance literature:

With rhodium hydrido (PEt₃)3 complex; 1-Phenylbut-1-en-3-one; In N,N-dimethyl-formamide; at 40 ℃; for 4h;

DOI:10.1016/0040-4039(94)02262-A

Reference yield: 90.0%

mannitol (69-65-8) → γ lactone of dl-mannonic acid (1128-23-0,1128-24-1,1198-69-2,1668-08-2,2426-46-2,2782-07-2,3158-30-3,3327-64-8,6322-07-2,10238-03-6,10366-82-2,18404-70-1,22430-23-5,23666-11-7,26301-79-1,29474-78-0,74464-44-1,78184-43-7,83602-36-2,119008-75-2,127997-10-8)

Guidance literature:

With 1-Phenylbut-1-en-3-one; rhodium hydrido (PEt₃)3 complex; In N,N-dimethyl-formamide; at 60 - 80 ℃;

DOI:10.1055/s-1998-1705

Reference yield: 60.0%

D-galactitol (608-66-2) → galactonic acid-4-lactone (1128-23-0,1128-24-1,1198-69-2,1668-08-2,2426-46-2,2782-07-2,3158-30-3,3327-64-8,6322-07-2,10238-03-6,10366-82-2,18404-70-1,22430-23-5,23666-11-7,26301-79-1,29474-78-0,74464-44-1,78184-43-7,83602-36-2,119008-75-2,127997-10-8)

Guidance literature:

With 1-Phenylbut-1-en-3-one; rhodium hydrido (PEt₃)3 complex; In N,N-dimethyl-formamide; Heating;

DOI:10.1055/s-1998-1705

upstream raw materials:

D-galactonic acid

D-galactonic acid hydrazide

O²,O³,O⁴,O⁶-tetramethyl-D-galactonic acid-lactone

D-Galactose

Downstream raw materials:

2,3,5,6-tetra-O-acetyl-D-galactono-1,4-lactone

D-galactitol

D-Galactose

1-Benzyl-2-D-galactonoyl-hydrazin