N-Ethyl-3,4-difluoroaniline

Base Information

Chemical Name:N-Ethyl-3,4-difluoroaniline
CAS No.:136491-15-1
Molecular Formula:C8H9F2N
Molecular Weight:157.163
Hs Code.:
European Community (EC) Number:825-378-1
DSSTox Substance ID:DTXSID10592906
Wikidata:Q82487266
Mol file:136491-15-1.mol

Synonyms:N-Ethyl-3,4-difluoroaniline;136491-15-1;BENZENAMINE, N-ETHYL-3,4-DIFLUORO-;N-(3,4-difluorophenyl)-N-ethylamine;Benzenamine, N-ethyl-3,4-difluoro- (9CI);SCHEMBL631579;DTXSID10592906;WWONUZXEGYMTKR-UHFFFAOYSA-N;MFCD11099404;AKOS000236912;SB75873;Benzenamine,N-ethyl-3,4-difluoro-(9ci);EN300-32881;Z334934070

Suppliers and Price of N-Ethyl-3,4-difluoroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-ethyl-3,4-difluoroaniline
100mg
$ 90.00

TRC
N-ethyl-3,4-difluoroaniline
50mg
$ 45.00

AK Scientific
N-Ethyl-3,4-difluoroaniline
250mg
$ 359.00

Total 2 raw suppliers

Chemical Property of N-Ethyl-3,4-difluoroaniline

Chemical Property:

Boiling Point:206.0±30.0 °C(Predicted)
PKA:4.48±0.33(Predicted)
PSA：12.03000
Density:1.174±0.06 g/cm3(Predicted)
LogP:2.46960
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:157.07030562
Heavy Atom Count:11
Complexity:119

Purity/Quality:

99%+ ^*data from raw suppliers

N-ethyl-3,4-difluoroaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCNC1=CC(=C(C=C1)F)F

Technology Process of N-Ethyl-3,4-difluoroaniline

There total 3 articles about N-Ethyl-3,4-difluoroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 136491-16-2
N-(3,4-Difluorphenyl)-N-ethyl-formamid

: 136491-15-1
N-ethyl-3,4-difluoroaniline

Guidance literature:: With hydrogenchloride; In water; for 2h; Heating;

Reference yield:

: 75-03-6
ethyl iodide

: 3863-11-4
3,4-difluoroaniline

: 136491-15-1
N-ethyl-3,4-difluoroaniline

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In toluene; at 90 ℃; for 24h;
DOI:10.1016/j.ejmech.2014.01.048

Reference yield:

: 3863-11-4
3,4-difluoroaniline

: 136491-15-1
N-ethyl-3,4-difluoroaniline

Guidance literature:: Multi-step reaction with 2 steps

1: 72.5 percent / conc. H₂SO₄ / 1.5 h / 175 °C

2: 77 percent / conc. HCl / H₂O / 2 h / Heating

With hydrogenchloride; sulfuric acid; In water;