Ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropanoate

Base Information

Chemical Name:Ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropanoate
CAS No.:139101-23-8
Molecular Formula:C11H10BrFO3
Molecular Weight:289.1
Hs Code.:2916399090
DSSTox Substance ID:DTXSID70576848
Nikkaji Number:J462.361D
Mol file:139101-23-8.mol

Synonyms:139101-23-8;Ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropanoate;2-Bromo-2-fluoro-3-oxo-3-phenylpropionic acid ethyl ester;Ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropanoate 98%;2-bromo-2-fluoro-3-oxo-3-phenylpropanoic acid ethyl ester;2-BROMO-2-FLUORO-3-OXO-3-PHENYL-PROPIONIC ACID ETHYL ESTER;DTXSID70576848;MFCD03844745;A807484;ethyl 2-bromo-2-fluoro-3-oxo-3-phenyl-propanoate

Suppliers and Price of Ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropionioate 98%
1 g
$ 663.00

American Custom Chemicals Corporation
ETHYL 2-BROMO-2-FLUORO-3-OXO-3-PHENYLPROPIONIOATE 95.00%
5G
$ 1766.00

American Custom Chemicals Corporation
ETHYL 2-BROMO-2-FLUORO-3-OXO-3-PHENYLPROPIONIOATE 95.00%
1G
$ 1063.76

Total 9 raw suppliers

Chemical Property of Ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropanoate

Chemical Property:

Vapor Pressure:0.00148mmHg at 25°C
Refractive Index:1.533
Boiling Point:296°C at 760 mmHg
Flash Point:132.8°C
PSA：43.37000
Density:1.5g/cm³
LogP:2.49310
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:287.97973
Heavy Atom Count:16
Complexity:276

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropionioate 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C(=O)C1=CC=CC=C1)(F)Br

Technology Process of Ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropanoate

There total 3 articles about Ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1479-22-7
ethyl 2-fluoro-3-oxo-3-phenylpropionate

: 139101-23-8
ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropionate

Guidance literature:: With bromine; In tetrachloromethane; for 1h; Ambient temperature;
DOI:10.1021/jo00033a058

Reference yield:

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 139101-23-8
ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropionate

Guidance literature:: Multi-step reaction with 2 steps

1: F₂

2: 94 percent / Br₂ / CCl₄ / 1 h / Ambient temperature

With bromine; fluorine; In tetrachloromethane;
DOI:10.1021/jo00033a058

Reference yield:

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 139101-23-8
ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropionate

Guidance literature:: Multi-step reaction with 2 steps

1: Selectfluor / acetonitrile / 2 h / Reflux

2: bromine / tetrachloromethane; dichloromethane / 0 - 20 °C

With bromine; Selectfluor; In tetrachloromethane; dichloromethane; acetonitrile;
DOI:10.1039/d0ob00267d