myo-Inositol, 2,4,5,6-tetrakis-O-(phenylmethyl)-

Base Information

• Chemical Name: myo-Inositol, 2,4,5,6-tetrakis-O-(phenylmethyl)-
• CAS No.: 141040-63-3
• Molecular Formula: C34H36O6
• Molecular Weight: 540.65
• Mol file: 141040-63-3.mol

Synonyms:myo-Inositol, 2,4,5,6-tetrakis-O-(phenylmethyl)-

Chemical Property of myo-Inositol, 2,4,5,6-tetrakis-O-(phenylmethyl)-

Chemical Property:

• PSA: 77.38000
• LogP: 5.06340

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of myo-Inositol, 2,4,5,6-tetrakis-O-(phenylmethyl)-

There total 49 articles about myo-Inositol, 2,4,5,6-tetrakis-O-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

benzyl bromide (100-39-0) + (±)-1,4,5-tri-O-benzyl-myo-inositol → (+/-)-1,3,4,5-tetra-O-benzyl-myo-inositol (131147-14-3,131233-76-6,132746-98-6,132747-00-3,141040-63-3,145553-67-9)

Guidance literature:

(±)-1,4,5-tri-O-benzyl-myo-inositol; With di(n-butyl)tin oxide; In methanol; toluene; at 130 ℃; for 3h;

benzyl bromide; With tetrabutylammomium bromide; In toluene; at 130 ℃; for 2.5h;

DOI:10.1021/jo026794c

Reference yield: 71.0%

benzyl bromide (100-39-0) + 2,4,6-tri-O-benzyl-myo-inositol (114828-08-9) → 1,2,4,6-tetra-O-benzyl-DL-myo-inositol (131147-14-3,131233-76-6,132746-98-6,132747-00-3,141040-63-3,145553-67-9)

Guidance literature:

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; In dichloromethane; at 45 ℃; for 16h;

DOI:10.1016/S0040-4039(00)97206-X

Reference yield: 35.0%

(+/-)-1,3,4,5-tetra-O-benzyl-2,6-di-O-allyl-myo-inositol → (+/-)-1,3,4,5-tetra-O-benzyl-myo-inositol (131147-14-3,131233-76-6,132746-98-6,132747-00-3,141040-63-3,145553-67-9)

Guidance literature:

With palladium 10% on activated carbon; water; toluene-4-sulfonic acid; In methanol; at 70 - 80 ℃; for 30h; Inert atmosphere;

DOI:10.1016/j.carres.2009.04.007

upstream raw materials:

(-)-1D-1,4-di-O-benzyl-myo-inositol

benzyl bromide

(+/-)-1,5,6-tri-O-benzyl-myo-inositol

(+/-)-1,3,4-tri-O-benzyl-myo-inositol

Downstream raw materials:

meso-1,3,4,5,6-penta-O-benzyl-myo-inositol

1-O-[2-azido-3-O-(4-bromobenzyl)-6-O-tert-butyldiphenylsilyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-2,4,5,6-tetra-O-benzyl-D-myo-inositol

3-O-[2-azido-3-O-(4-bromobenzyl)-6-O-tert-butyldiphenylsilyl-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-2,4,5,6-tetra-O-benzyl-D-myo-inositol

2,4,5,6-Tetra-O-benzyl-myo-inositol 1,3-bis(sodium benzyl phosphate)