Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate

Base Information

Chemical Name:Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate
CAS No.:141546-97-6
Molecular Formula:C7H12 F2 O4
Molecular Weight:198.16
Hs Code.:2918990090
DSSTox Substance ID:DTXSID40374515
Mol file:141546-97-6.mol

Synonyms:141546-97-6;Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate;ethyl 3-ethoxy-2,2-difluoro-3-hydroxypropanoate;3-Ethoxy-2,2-difluoro-3-hydroxypropionic Acid Ethyl Ester;DTXSID40374515;DCDGEVPPIDIMON-UHFFFAOYSA-N;MFCD00718642;AKOS006228546;SB83874;CS-0361519;E0547;FT-0643329;T71760;A807775;ethyl 3-ethoxy-2,2-difluoro-3-hydroxy-propanoate;J-007515;4-HYDROXY-4-METHYL-BIPHENYL-3-CARBOXYLICACID

Suppliers and Price of Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate
100mg
$ 175.00

TCI Chemical
Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate >83.0%(GC)
1g
$ 345.00

Crysdot
Ethyl3-ethoxy-2,2-difluoro-3-hydroxypropanoate 95+%
5g
$ 671.00

American Custom Chemicals Corporation
Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate 95.00%
1G
$ 804.11

AK Scientific
Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate
1g
$ 479.00

AHH
Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate 98%
5g
$ 418.00

Total 14 raw suppliers

Chemical Property of Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate

Chemical Property:

Vapor Pressure:0.00227mmHg at 25°C
Refractive Index:1.403
Boiling Point:256.7°Cat760mmHg
PKA:11.02±0.20(Predicted)
Flash Point:109.1°C
PSA：55.76000
Density:1.217g/cm³
LogP:0.53970
Storage Temp.:Refrigerator
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:198.07036518
Heavy Atom Count:13
Complexity:172

Purity/Quality:

98% ^*data from raw suppliers

Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(C(C(=O)OCC)(F)F)O

Technology Process of Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate

There total 2 articles about Ethyl 3-Ethoxy-2,2-difluoro-3-hydroxypropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 141546-96-5
ethyl 3-ethoxy-2,2-difluoro-3-(dimethylamino)propionate

: 141546-97-6
ethyl 3-ethoxy-2,2-difluoro-3-hydroxypropionate

Guidance literature:: With sulfuric acid; In ethanol; for 0.166667h; Ambient temperature;
DOI:10.1039/c39920000540

Reference yield:

: 141546-96-5
ethyl 3-ethoxy-2,2-difluoro-3-(dimethylamino)propionate

: 141546-97-6
ethyl 3-ethoxy-2,2-difluoro-3-hydroxypropionate

: 143698-04-8
2,2-Difluoro-3,3-dihydroxy-propionic acid ethyl ester

Guidance literature:: With boron trifluoride diethyl etherate; water; Multistep reaction; 1.) CH₂Cl₂, 0 deg C, 2.) CH₂Cl₂, 0 deg C;
DOI:10.1246/cl.1992.1377