4-Methyl-5H-cyclopenta[c]pyridin-7(6H)-one

Base Information

Chemical Name:4-Methyl-5H-cyclopenta[c]pyridin-7(6H)-one
CAS No.:147646-28-4
Molecular Formula:C₉H₉NO
Molecular Weight:147.177
Hs Code.:
DSSTox Substance ID:DTXSID301226892
Mol file:147646-28-4.mol

Synonyms:147646-28-4;4-methyl-5,6-dihydrocyclopenta[c]pyridin-7-one;7H-Cyclopenta[c]pyridin-7-one,5,6-dihydro-4-methyl-(9CI);DTXSID301226892;4-Methyl-5H-cyclopenta[c]pyridin-7(6H)-one;4-Methyl-5,6-dihydro-7H-cyclopenta[c]pyridin-7-one;5,6-Dihydro-4-methyl-7H-cyclopenta[c]pyridin-7-one

Suppliers and Price of 4-Methyl-5H-cyclopenta[c]pyridin-7(6H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-Methyl-5H-cyclopenta[c]pyridin-7(6H)-one

Chemical Property:

Boiling Point:283.0±19.0 °C(Predicted)
PKA:4.38±0.20(Predicted)
PSA：29.96000
Density:1.181±0.06 g/cm3(Predicted)
LogP:1.51890
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:147.068413911
Heavy Atom Count:11
Complexity:178

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN=CC2=C1CCC2=O

Technology Process of 4-Methyl-5H-cyclopenta[c]pyridin-7(6H)-one

There total 2 articles about 4-Methyl-5H-cyclopenta[c]pyridin-7(6H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-Methyl-7-oxo-6,7-dihydro-5H-[2]pyrindine-6-carboxylic acid

: 147646-28-4
4-methyl-5,6-dihydro-2-pyrindin-7-one

Guidance literature:: With sodium chloride; In tetrahydrofuran; water; Yield given; Heating;
DOI:10.1021/jo00063a043

Reference yield:

: 29681-45-6
5-methylnicotinic acid methyl ester

: 147646-28-4
4-methyl-5,6-dihydro-2-pyrindin-7-one

Guidance literature:: Multi-step reaction with 4 steps

2: sulfur / xylene / Heating

3: 1.) sodium hydride, 2.) 10 percent HCl / 1.) THF, reflux, 2.) 0 deg C

4: NaCl / tetrahydrofuran; H₂O / Heating

With hydrogenchloride; sodium hydride; sulfur; sodium chloride; In tetrahydrofuran; water; xylene;
DOI:10.1021/jo00063a043

Reference yield:

: 1779-49-3
Methyltriphenylphosphonium bromide

: 147646-28-4
4-methyl-5,6-dihydro-2-pyrindin-7-one

: 147646-29-5
4-methyl-7-methylene-6,7-dihydro-2(5H)-pyrindine

Guidance literature:: With potassium tert-butylate; Yield given. Multistep reaction; 1.) toluene, room temperature, overnight, 2.) 1 h;
DOI:10.1021/jo00063a043