tert-Butyl(dibromomethyl)dimethylsilane

Base Information

• Chemical Name: tert-Butyl(dibromomethyl)dimethylsilane
• CAS No.: 148259-35-2
• Molecular Formula: C7H16 Br2 Si
• Molecular Weight: 288.098
• DSSTox Substance ID: DTXSID80402760
• Nikkaji Number: J1.377.662H
• Wikidata: Q82206233
• Mol file: 148259-35-2.mol

Synonyms:148259-35-2;tert-Butyl(dibromomethyl)dimethylsilane;tert-butyl-(dibromomethyl)-dimethylsilane;Silane, (dibromomethyl)(1,1-dimethylethyl)dimethyl-;DTXSID80402760;(tert-Butyldimethylsilyl)dibromomethane;AKOS025294544;AS-80330;tert-Butyl(dibromomethyl)dimethylsilane, 97%;E77559

Chemical Property of tert-Butyl(dibromomethyl)dimethylsilane

Chemical Property:

• Vapor Pressure: 0.19mmHg at 25°C
• Refractive Index: n20/D 1.5059(lit.)
• Boiling Point: 60 °C1 mm Hg(lit.)
• Flash Point: 198 °F
• PSA: 0.00000
• Density: 1.423 g/mL at 25 °C(lit.)
• LogP: 4.56990
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 287.93675
• Heavy Atom Count: 10
• Complexity: 113

Purity/Quality:

95%, ^*data from raw suppliers

tert-Butyl(dibromomethyl)dimethylsilane 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)[Si](C)(C)C(Br)Br

Technology Process of tert-Butyl(dibromomethyl)dimethylsilane

There total 1 articles about tert-Butyl(dibromomethyl)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

tert-butyldimethylsilyl chloride (18162-48-6) + 1,1-dibromomethane (74-95-3) → tert-butyldimethyl(dibromomethyl)silane (148259-35-2)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

DOI:10.1016/S0040-4039(00)91972-5

Reference yield: 95.0%

allylmagnesium bromide (2622-05-1) + 4-methoxybenzonitrile (874-90-8) + tert-butyldimethyl(dibromomethyl)silane (148259-35-2) → 2,3-diallyl-2-(t-butyldimethylsilyl)-3-(4-methoxyphenyl)aziridine

Guidance literature:

tert-butyldimethyl(dibromomethyl)silane; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 1h;

4-methoxybenzonitrile; In tetrahydrofuran;

allylmagnesium bromide; In tetrahydrofuran;

DOI:10.1021/ja047708o

Reference yield: 84.0%

N-(benzylidene)-p-methylbenzenesulfonamide (51608-60-7) + tert-butyldimethyl(dibromomethyl)silane (148259-35-2) → N-[2,2-dibromo-2-(tert-butyl-dimethyl-silanyl)-1-phenyl-ethyl]-4-methyl-benzenesulfonamide

Guidance literature:

tert-butyldimethyl(dibromomethyl)silane; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.5h;

N-(benzylidene)-p-methylbenzenesulfonamide; In tetrahydrofuran; at -78 - 20 ℃; for 2h;

DOI:10.1021/ol048092a

upstream raw materials:

tert-butyldimethylsilyl chloride

1,1-dibromomethane

Downstream raw materials:

2,2-dibromo-2-(tert-butyldimethylsilyl)-2-phenylethanol

1,1-dibromo-2-(tert-butyldimethylsiloxy)-2-phenylethane

tert-Butyl-((E)-1-dibromomethyl-3-phenyl-allyloxy)-dimethyl-silane

1,1-dibromo-2-tert-butyldimethylsiloxy-2-phenylpropane