Technology Process of 3-(Methylsulfonyl)benzamidine hydrochloride
There total 5 articles about 3-(Methylsulfonyl)benzamidine hydrochloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.331 g / m-chloroperoxybenzoic acid / CH2Cl2 / 5.66 h / 0 - 20 °C
2: 1.) MeONa, 2.) NH4Cl / 1.) MeOH, 45 deg C, 23 h, 2.) MeOH, 45 deg C, 24 h
With
sodium methylate; ammonium chloride; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
DOI:10.1021/ja00070a003
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) HCl, aq. NaNO2, 2.) Na2CO3 / 2.) toluene, from 0 deg C to RT, 120 min
2: 1.331 g / m-chloroperoxybenzoic acid / CH2Cl2 / 5.66 h / 0 - 20 °C
3: 1.) MeONa, 2.) NH4Cl / 1.) MeOH, 45 deg C, 23 h, 2.) MeOH, 45 deg C, 24 h
With
hydrogenchloride; sodium methylate; sodium carbonate; ammonium chloride; 3-chloro-benzenecarboperoxoic acid; sodium nitrite;
In
dichloromethane;
DOI:10.1021/ja00070a003
- Guidance literature:
-
With
hydrogenchloride; ethanol; chloroform;
Behandeln des nach mehreren Tagen isolierten Reaktionsprodukts mit aethanol. Ammoniak;
DOI:10.1039/jr9450000633