Technology Process of N-(2-FORMYL-5,8-DIOXO-5,8-DIHYDROQUINOLIN-7-YL)ACETAMIDE
There total 8 articles about N-(2-FORMYL-5,8-DIOXO-5,8-DIHYDROQUINOLIN-7-YL)ACETAMIDE which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
selenium(IV) oxide;
In
1,4-dioxane; water;
for 9h;
Heating;
DOI:10.1021/jo00077a032
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: H2; HCl / Pd/C / H2O / 15 h / 20 °C / 1551.44 Torr
2.1: NaOAc; Ma2CO3 / 2.5 h / 0 - 20 °C
2.2: methanol / 0.5 h / Heating
3.1: 71 percent / K2Cr2O7; AcOH; H2O / 24 h / 20 °C
4.1: 91 percent / SeO2 / dioxane; H2O / Heating
With
hydrogenchloride; potassium dichromate; selenium(IV) oxide; water; hydrogen; sodium acetate; sodium carbonate; acetic acid;
palladium on activated charcoal;
In
1,4-dioxane; water;
DOI:10.1021/ol035381a
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 72 percent / HNO3, H2SO4 / 2 h / 0 - 5 °C
2: 98 percent / H2, aq. HCl / Pd-C / 15 h / 1551.4 Torr
3: 85 percent / NaOAc, Na2SO3 / H2O / 3.25 h
4: 60 percent / aq. K2Cr2O7, AcOH / 15 h
5: 91 percent / SeO2
With
hydrogenchloride; potassium dichromate; selenium(IV) oxide; sulfuric acid; hydrogen; nitric acid; sodium acetate; acetic acid; sodium sulfite;
palladium on activated charcoal;
In
water;
DOI:10.1021/jo960794t
