2-Methyloctahydro-6H-pyrazino[1,2-c]pyrimidin-6-one

Base Information

Chemical Name:2-Methyloctahydro-6H-pyrazino[1,2-c]pyrimidin-6-one
CAS No.:151733-63-0
Molecular Formula:C₈H₁₅N₃O
Molecular Weight:169.227
Hs Code.:
DSSTox Substance ID:DTXSID80569160
Mol file:151733-63-0.mol

Synonyms:151733-63-0;2-Methyloctahydro-6H-pyrazino[1,2-c]pyrimidin-6-one;2-methyl-3,4,7,8,9,9a-hexahydro-1H-pyrazino[1,2-c]pyrimidin-6-one;2-Methylhexahydro-1H-pyrazino[1,2-c]pyrimidin-6(2H)-one;6H-Pyrazino[1,2-c]pyrimidin-6-one,octahydro-2-methyl-(9CI);SCHEMBL16565924;DTXSID80569160;MB69116;2-METHYLHEXAHYDRO-PYRAZINO[1,2-C]PYRIMIDIN-6(2H)-ONE

Suppliers and Price of 2-Methyloctahydro-6H-pyrazino[1,2-c]pyrimidin-6-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
octahydro-2-methyl-6H-Pyrazino[1,2-c]pyrimidin-6-one 97.00%
25G
$ 12900.00

AccelPharmtech
octahydro-2-methyl-6H-Pyrazino[1,2-c]pyrimidin-6-one 97.00%
5G
$ 6840.00

AccelPharmtech
octahydro-2-methyl-6H-Pyrazino[1,2-c]pyrimidin-6-one 97.00%
1G
$ 3960.00

Total 1 raw suppliers

Chemical Property of 2-Methyloctahydro-6H-pyrazino[1,2-c]pyrimidin-6-one

Chemical Property:

PSA：39.07000
LogP:-0.76850
XLogP3:-0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:169.121512110
Heavy Atom Count:12
Complexity:195

Purity/Quality:: octahydro-2-methyl-6H-Pyrazino[1,2-c]pyrimidin-6-one 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN2C(C1)CCNC2=O

Technology Process of 2-Methyloctahydro-6H-pyrazino[1,2-c]pyrimidin-6-one

There total 5 articles about 2-Methyloctahydro-6H-pyrazino[1,2-c]pyrimidin-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 151733-62-9
octahydro-6H-pyrazino<1,2-c>pyrimidin-6-one

: 151733-63-0
2-methyl-octahydro-6H-pyrazino<1,2-c>pyrimidin-6-one

Guidance literature:: With formic acid; at 80 ℃; for 8h;

Reference yield:

: 151733-60-7
ethyl N-<2-(1,4-dibenzyl-2-piperazinyl)ethyl>carbamate

: 151733-63-0
2-methyl-octahydro-6H-pyrazino<1,2-c>pyrimidin-6-one

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / H₂ / 10percent Pd-C / acetic acid

2: 60 percent / NaOEt / ethanol / warming

3: 70 percent / 98percent HCO₂H / 8 h / 80 °C

With formic acid; hydrogen; sodium ethanolate; palladium on activated charcoal; In ethanol; acetic acid;

Reference yield:

: 70403-11-1
2-(1,4-dibenzyl-2-piperazinyl)acetonitrile

: 151733-63-0
2-methyl-octahydro-6H-pyrazino<1,2-c>pyrimidin-6-one

Guidance literature:: Multi-step reaction with 5 steps

1: 93 percent / H₂ / Raney nickel / methanol

2: 84 percent / Et₃N / CH₂Cl₂ / 1) 0 deg C, 4 h, 2) r. t., 12 h

3: 80 percent / H₂ / 10percent Pd-C / acetic acid

4: 60 percent / NaOEt / ethanol / warming

5: 70 percent / 98percent HCO₂H / 8 h / 80 °C

With formic acid; hydrogen; sodium ethanolate; triethylamine; palladium on activated charcoal; nickel; In methanol; ethanol; dichloromethane; acetic acid;