2,6-DIMETHYLBENZAMIDE

Base Information

• Chemical Name: 2,6-DIMETHYLBENZAMIDE
• CAS No.: 55321-98-7
• Molecular Formula: C9H11NO
• Molecular Weight: 149.192
• Hs Code.: 2924299090
• Mol file: 55321-98-7.mol

Synonyms:2,6-DIMETHYLBENZAMIDE;Benzamide, 2,6-dimethyl- (6CI, 7CI, 9CI)

Chemical Property of 2,6-DIMETHYLBENZAMIDE

Chemical Property:

• Melting Point: 136 °C
• Boiling Point: 233.0±29.0 °C(Predicted)
• PKA: 16.03±0.50(Predicted)
• PSA: 43.09000
• Density: 1.060±0.06 g/cm3(Predicted)
• LogP: 2.10260

Purity/Quality:

99% ^*data from raw suppliers

2,6-Dimethylbenzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-DIMETHYLBENZAMIDE

There total 12 articles about 2,6-DIMETHYLBENZAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2,6-Dimethylbenzoylurea (124808-91-9) → 2,6-dimethylbenzamide (55321-98-7)

Guidance literature:

With water; sodium carbonate; for 4h; Heating;

DOI:10.1016/S0014-827X(98)00057-3

Reference yield: 40.0%

Acetanilid (103-84-4) + urethane (51-79-6) → 2-acetamidobenzamide (33809-77-7) + 2,6-dimethylbenzamide (55321-98-7)

Guidance literature:

With aluminium trichloride; In xylene; for 4.5h; Heating;

DOI:10.1055/s-1981-29667

Reference yield: 35.0%

N-methyl-N,2-diphenylacetamide (40669-47-4) + urethane (51-79-6) → N-methyl-N-phenylacetyl-anthranilic acid amide (21411-08-5) + 2,6-dimethylbenzamide (55321-98-7)

Guidance literature:

With aluminium trichloride; In xylene; for 4.5h; Heating;

DOI:10.1055/s-1981-29667

upstream raw materials:

2,6-dimethylbenzonitrile

2,6-dimethylbenzoyl chloride

m-xylene

urethane

Downstream raw materials:

2,6-dimethylbenzoic acid

methyl (2,6-dimethylphenyl)carbamate

7-Methyl-2,3-dihydroisoindole-1-one

3-Methylphthalimide

Refernces

• 1、 Adolphe-Pierre,Menager,Tombret,Verite,Lepage,Lafont. "Chemical oxidation of an anticonvulsant N-(5'-methylisoxazol-3-yl) 2,6- dimethylbenzamide (D2916)". . p. 513 - 518. Retrieved 2007/10/03.
• 2、 Chakraborty, D. P.,Mandal, Anchal Kanti,Roy, Swapan Kumar. "Ethyl Carbamate as an Aminocarbonylating Agent: Modification of Gattermann's Amidation Reaction". . p. 977 - 979. Retrieved 2007/10/02.