N,N-dimethyl-2-(5-nitro-1H-indol-3-yl)ethanamine

Base Information

Chemical Name:N,N-dimethyl-2-(5-nitro-1H-indol-3-yl)ethanamine
CAS No.:69937-13-9
Molecular Formula:C12H15N3O2
Molecular Weight:233.27
Hs Code.:
DSSTox Substance ID:DTXSID40359185
Wikidata:Q82140260
Mol file:69937-13-9.mol

Synonyms:69937-13-9;N,N-dimethyl-2-(5-nitro-1H-indol-3-yl)ethanamine;3-(2-DIMETHYLAMINOETHYL)-5-NITROINDOLE;Oprea1_262885;SCHEMBL2535250;DTXSID40359185;WNAXXOOIDCPHIB-UHFFFAOYSA-N;STK370593;AKOS005446116;5-nitro-3-[2-(dimethylamino) ethyl]indole

Suppliers and Price of N,N-dimethyl-2-(5-nitro-1H-indol-3-yl)ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N,N-Dimethyl-5-nitrotryptamine
500mg
$ 403.00

American Custom Chemicals Corporation
3-(2-DIMETHYLAMINOETHYL)-5-NITROINDOLE 95.00%
5MG
$ 504.20

Total 3 raw suppliers

Chemical Property of N,N-dimethyl-2-(5-nitro-1H-indol-3-yl)ethanamine

Chemical Property:

Melting Point:166-169°C
PSA：64.85000
LogP:2.70340
Storage Temp.:-20°C Freezer
Solubility.:Chloroform, Dichloromethane, Methanol
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:233.116426730
Heavy Atom Count:17
Complexity:277

Purity/Quality:

95% ^*data from raw suppliers

N,N-Dimethyl-5-nitrotryptamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCC1=CNC2=C1C=C(C=C2)[N+](=O)[O-]

Technology Process of N,N-dimethyl-2-(5-nitro-1H-indol-3-yl)ethanamine

There total 6 articles about N,N-dimethyl-2-(5-nitro-1H-indol-3-yl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 166171-97-7
3-(2-bromoethyl)-5-nitro-1H-indole

: 69937-13-9
3-(2-dimethylaminoethyl)-5-nitroindole

Guidance literature:: With dimethyl amine; In ethanol;

Reference yield:

: 858231-11-5
3-(2-chloro-ethyl)-5-nitro-indole

: 124-40-3
dimethyl amine

: 69937-13-9
3-(2-dimethylaminoethyl)-5-nitroindole

Guidance literature:: With ethanol;
DOI:10.1021/ja01104a029

Reference yield:

: 6146-52-7
5-nitroindole

: 69937-13-9
3-(2-dimethylaminoethyl)-5-nitroindole

Guidance literature:: Multi-step reaction with 3 steps

1: phthalimide / diethyl ether / 72 h / Ambient temperature

2: diethyl ether / 1 h / Ambient temperature

3: 1.) borane, 2.) CsF, sodium carbonate / 1.) THF, RT, 16 h, 2.) EtOH, reflux, 16 h

With phthalimide; borane; sodium carbonate; cesium fluoride; In diethyl ether;
DOI:10.1080/00397919308020402