Furo[3,2-C]pyridine-7-carbonitrile

Base Information

Chemical Name:Furo[3,2-C]pyridine-7-carbonitrile
CAS No.:603302-76-7
Molecular Formula:C8H4N2O
Molecular Weight:144.13016
Hs Code.:
DSSTox Substance ID:DTXSID90591952
Wikidata:Q82485825
Mol file:603302-76-7.mol

Synonyms:FURO[3,2-C]PYRIDINE-7-CARBONITRILE;603302-76-7;Furo[3,2-c]pyridine-7-carbonitrile (9CI);SCHEMBL2259743;DTXSID90591952;SCAPHSPFYDTKEV-UHFFFAOYSA-N;DB-265137

Suppliers and Price of Furo[3,2-C]pyridine-7-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Furo[3,2-c]pyridine-7-carbonitrile 95+%
10g
$ 1935.00

Crysdot
Furo[3,2-c]pyridine-7-carbonitrile 95+%
5g
$ 1439.00

Crysdot
Furo[3,2-c]pyridine-7-carbonitrile 95+%
1g
$ 743.00

AccelPharmtech
Furo[3,2-c]pyridine-7-carbonitrile 97.00%
25G
$ 14600.00

AccelPharmtech
Furo[3,2-c]pyridine-7-carbonitrile 97.00%
5G
$ 7730.00

Total 1 raw suppliers

Chemical Property of Furo[3,2-C]pyridine-7-carbonitrile

Chemical Property:

PSA：49.82000
LogP:1.69948
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:144.032362755
Heavy Atom Count:11
Complexity:196

Purity/Quality:: Furo[3,2-c]pyridine-7-carbonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=COC2=C(C=NC=C21)C#N

Technology Process of Furo[3,2-C]pyridine-7-carbonitrile

There total 4 articles about Furo[3,2-C]pyridine-7-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 544-92-3
copper(I) cyanide

: 603300-96-5
7-bromofuro[3,2-c]pyridine

: 603302-76-7
furo[3,2-c]pyridine-7-carbonitrile

Guidance literature:: With copper(l) iodide; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2004.12.063

Reference yield:

: 26956-43-4
5H-furo[3,2-c]pyridin-4-one

: 603302-76-7
furo[3,2-c]pyridine-7-carbonitrile

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / NBS

2: 50 percent / POBr₃

3: 75 percent / Pd(PPh₃)4; HCOONa

4: 94 percent / CuI / dimethylformamide

With N-Bromosuccinimide; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium formate; phosphorus(V) oxybromide; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2004.12.063

Reference yield:

: 603301-06-0
4,7-dibromofuro[3,2-c]pyridine

: 603302-76-7
furo[3,2-c]pyridine-7-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / Pd(PPh₃)4; HCOONa

2: 94 percent / CuI / dimethylformamide

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium formate; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2004.12.063