7,7-Dimethoxyheptanal

Base Information

• Chemical Name: 7,7-Dimethoxyheptanal
• CAS No.: 60090-77-9
• Molecular Formula: C9H18O3
• Molecular Weight: 174.24
• Hs Code.: 2912499000
• Mol file: 60090-77-9.mol

Synonyms:7,7-dimethoxy-heptanal;Heptanal,7,7-dimethoxy;

Chemical Property of 7,7-Dimethoxyheptanal

Chemical Property:

• PSA: 35.53000
• LogP: 1.75470

Purity/Quality:

7,7-DIMETHOXYHEPTANAL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7,7-Dimethoxyheptanal

There total 5 articles about 7,7-Dimethoxyheptanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methanol (67-56-1) + Cycloheptene (628-92-2,45509-99-7) → 7,7-dimethoxyheptanal (60090-77-9)

Guidance literature:

methanol; Cycloheptene; With ozone; In dichloromethane; at -78 ℃;

With toluene-4-sulfonic acid; In dichloromethane; at -78 - 20 ℃; for 1h; Further stages.;

DOI:10.1039/b615378j

Reference yield:

Cycloheptene (628-92-2,45509-99-7) → 7,7-dimethoxyheptanal (60090-77-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) O₃, 2.) p-toluenesulfonic acid / 1.) ozonolysis, 2.) 1.5 h, room temperature

2: NaHCO₃, dimethylsulfide

With dimethylsulfide; sodium hydrogencarbonate; toluene-4-sulfonic acid; ozone;

DOI:10.1016/S0040-4039(00)87729-1

Reference yield:

dimethylsulfide (75-18-3) + Cycloheptene (628-92-2,45509-99-7) → 7,7-dimethoxyheptanal (60090-77-9)

Guidance literature:

With sodium hydrogencarbonate; toluene-4-sulfonic acid; ozone; Yield given. Multistep reaction;

DOI:10.1021/ja00226a041

upstream raw materials:

methanol

Cycloheptene

dimethylsulfide

Downstream raw materials:

trans-2-Carbomethoxymethylcyclohexan-1-carboxaldehyd

yohimbane

(S)-3-(1-carbamoyl-1,1-diphenylmethyl)-1-(7,7-dimethoxyhept-1-yl)pyrrolidine

Pent-4-enoic acid (1R,7R)-7-benzyloxy-1-pentyl-dec-9-enyl ester

Refernces

• 1、 He, Jing,Tchabanenko, Kirill,Adlington, Robert M.,Cowley, Andrew R.,Baldwin, Jack E.. "New domino silyl enol ether reactions in the synthesis of a tetrodecamycin fragment". . p. 4003 - 4013. Retrieved 2006.
• 2、 Douelle, Frederic,Capes, Amy S.,Greaney, Michael F.. "Highly diastereoselective synthesis of vicinal quaternary and tertiary stereocenters using the iodo-aldol cyclization". . p. 1931 - 1934. Retrieved 2008/02/02.