Ethyl 6-aminopicolinate

Base Information

Chemical Name:Ethyl 6-aminopicolinate
CAS No.:69142-64-9
Molecular Formula:C8H10N2O2
Molecular Weight:166.18
Hs Code.:2933399090
European Community (EC) Number:833-611-3
DSSTox Substance ID:DTXSID50474772
Nikkaji Number:J1.404.945B
Wikidata:Q72472624
Mol file:69142-64-9.mol

Synonyms:ethyl 6-aminopicolinate;69142-64-9;ETHYL 6-AMINOPYRIDINE-2-CARBOXYLATE;6-Aminopyridine-2-carboxylic acid ethyl ester;2-Pyridinecarboxylic acid, 6-amino-, ethyl ester;MFCD01009842;6-Aminopyridine-2-carboxylicacidethylester;ethyl 6-amino-2-pyridinecarboxylate;2-Amino-6-carbethoxypyridine;2-carbethoxy-6-iminopyridine;SCHEMBL465841;DTXSID50474772;DTYDENRYZSEGNL-UHFFFAOYSA-N;6-Aminopicolinic Acid Ethyl Ester;AKOS006274782;CS-W005977;FS-3371;AM101148;SY053217;E1213;FT-0716810;2-aminopyridine-6-carboxylic acid ethyl ester;EN300-343511;A836366;J-521171;F8885-0183

Suppliers and Price of Ethyl 6-aminopicolinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl6-Aminopicolinate
500mg
$ 130.00

TCI Chemical
Ethyl 6-Aminopyridine-2-carboxylate >98.0%(GC)(T)
5g
$ 418.00

TCI Chemical
Ethyl 6-Aminopyridine-2-carboxylate >98.0%(GC)(T)
1g
$ 139.00

Crysdot
Ethyl6-aminopicolinate 98%
10g
$ 178.00

Chemenu
6-Aminopyridine-2-carboxylicacidethylester 98%
25g
$ 486.00

Chemenu
6-Aminopyridine-2-carboxylicacidethylester 98%
10g
$ 292.00

Chemenu
6-Aminopyridine-2-carboxylicacidethylester 98%
5g
$ 195.00

Apolloscientific
6-Aminopyridine-2-carboxylicacidethylester 95%
250mg
$ 203.00

Apolloscientific
6-Aminopyridine-2-carboxylicacidethylester 95%
1g
$ 580.00

American Custom Chemicals Corporation
6-AMINOPYRIDINE-2-CARBOXYLICACIDETHYLESTER 95.00%
5MG
$ 505.43

Total 37 raw suppliers

Chemical Property of Ethyl 6-aminopicolinate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:56-58℃
Refractive Index:1.559
Boiling Point:329.602 °C at 760 mmHg
PKA:1.87±0.10(Predicted)
Flash Point:153.138 °C
PSA：65.21000
Density:1.193 g/cm³
LogP:1.42170
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Solubility.:soluble in Methanol
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:166.074227566
Heavy Atom Count:12
Complexity:161

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ethyl6-Aminopicolinate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=NC(=CC=C1)N

Technology Process of Ethyl 6-aminopicolinate

There total 10 articles about Ethyl 6-aminopicolinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 23628-31-1
6-aminopicolinic acid

: 64-17-5
ethanol

: 69142-64-9
ethyl 6-aminopicolinate

Guidance literature:: 6-aminopicolinic acid; ethanol; With thionyl chloride; at 0 ℃; Reflux;

With sodium carbonate; In water; pH=9;

Reference yield: 50.0%

: 64-17-5
ethanol

: 258497-21-1
6-[(tert-butoxycarbonyl)amino]-2-pyridinecarboxylic acid

: 69142-64-9
ethyl 6-aminopicolinate

Guidance literature:: With sulfuric acid; for 5h; Inert atmosphere; Reflux;
DOI:10.1080/10610278.2010.483732

Reference yield:

: 23628-31-1
6-aminopicolinic acid

: 69142-64-9
ethyl 6-aminopicolinate

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride / 13 h / 20 - 45 °C

2: 0.50 g / 1 h / Heating

With oxalyl dichloride; 1: Substitution / 2: Esterification;
DOI:10.1016/S0040-4020(00)00733-X