tert-Butyl 3-amino-5-methyl-1H-pyrazole-1-carboxylate

Base Information

Chemical Name:tert-Butyl 3-amino-5-methyl-1H-pyrazole-1-carboxylate
CAS No.:578008-32-9
Molecular Formula:C9H15N3O2
Molecular Weight:197.237
Hs Code.:2933199090
European Community (EC) Number:887-631-2
Mol file:578008-32-9.mol

Synonyms:578008-32-9;tert-Butyl 3-amino-5-methyl-1H-pyrazole-1-carboxylate;3-Amino-1-Boc-5-methyl-1H-pyrazole;1H-Pyrazole-1-carboxylicacid,3-amino-5-methyl-,1,1-dimethylethylester;tert-butyl 3-amino-5-methylpyrazole-1-carboxylate;MFCD13252375;SCHEMBL161429;GJDCNROAKOCYIQ-UHFFFAOYSA-N;1-boc-3-amino-5-methyl-pyrazole;1-Boc-3-amino-5-methyl-1H-pyrazole;AKOS024258768;AKOS037647138;AS-72542;SY060940;CS-0036055;W12764;EN300-7364853;A935450;tert-Butyl3-amino-5-methyl-1H-pyrazole-1-carboxylate;Z1216817739;1,1-Dimethylethyl 3-amino-5-methyl-1H-pyrazole-1-carboxylate;3-Amino-5-methyl-pyrazole-1-carboxylic acid tert-butyl ester;1H-Pyrazole-1-carboxylic acid,3-amino-5-methyl-,tert-butyl ester;tert-butyl 3-imino-5-methyl-2,3-dihydro-1H-pyrazole-1-carboxylate

Suppliers and Price of tert-Butyl 3-amino-5-methyl-1H-pyrazole-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-Butyl3-Amino-5-methyl-1H-pyrazole-1-carboxylate
50mg
$ 110.00

Crysdot
tert-Butyl3-amino-5-methyl-1H-pyrazole-1-carboxylate 95+%
10g
$ 525.00

Crysdot
tert-Butyl3-amino-5-methyl-1H-pyrazole-1-carboxylate 95+%
5g
$ 317.00

Crysdot
tert-Butyl3-amino-5-methyl-1H-pyrazole-1-carboxylate 95+%
1g
$ 99.00

Alichem
tert-Butyl3-amino-5-methyl-1H-pyrazole-1-carboxylate
10g
$ 545.90

Alichem
tert-Butyl3-amino-5-methyl-1H-pyrazole-1-carboxylate
5g
$ 310.40

AK Scientific
tert-Butyl3-amino-5-methyl-1H-pyrazole-1-carboxylate
1g
$ 294.80

Total 15 raw suppliers

Chemical Property of tert-Butyl 3-amino-5-methyl-1H-pyrazole-1-carboxylate

Chemical Property:

Boiling Point:322.7±34.0 °C(Predicted)
PKA:2.89±0.11(Predicted)
PSA：70.14000
Density:1.18±0.1 g/cm3(Predicted)
LogP:2.13810
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:197.116426730
Heavy Atom Count:14
Complexity:225

Purity/Quality:

99%, ^*data from raw suppliers

tert-Butyl3-Amino-5-methyl-1H-pyrazole-1-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NN1C(=O)OC(C)(C)C)N

Technology Process of tert-Butyl 3-amino-5-methyl-1H-pyrazole-1-carboxylate

There total 8 articles about tert-Butyl 3-amino-5-methyl-1H-pyrazole-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 31230-17-8
3-methyl-5-aminopyrazole

: 24424-99-5
di-tert-butyl dicarbonate

: 1065204-79-6
tert-butyl 5-amino-3-methyl-1H-pyrazole-1-carboxylate

: 578008-32-9
tert-butyl 3-amino-5-methyl-1H-pyrazole-1-carboxylate

Guidance literature:: With sodium hydroxide; In dichloromethane; at 20 ℃; for 19h; Inert atmosphere;
DOI:10.1016/j.bmc.2016.03.042

Reference yield: 76.0%

: 24424-95-1
di-tert-butyl tricarbonate

: 31230-17-8
3-methyl-5-aminopyrazole

: 578008-32-9
tert-butyl 3-amino-5-methyl-1H-pyrazole-1-carboxylate

Guidance literature:: With triethylamine; In 1,4-dioxane; for 3h; Schlenk technique; Reflux;
DOI:10.3390/molecules27020360

Reference yield: 59.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 1065204-79-6
tert-butyl 5-amino-3-methyl-1H-pyrazole-1-carboxylate

: 578008-32-9
tert-butyl 3-amino-5-methyl-1H-pyrazole-1-carboxylate

Guidance literature:: 3-methyl-5-aminopyrazole; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

di-tert-butyl dicarbonate; In tetrahydrofuran; at 20 ℃; for 2h;