AMYLOID BETA/A4 PROTEIN PRECURSOR770 (586-595) (HUMAN, MOUSE, RAT)

Base Information

• Chemical Name: AMYLOID BETA/A4 PROTEIN PRECURSOR770 (586-595) (HUMAN, MOUSE, RAT)
• CAS No.: 566173-30-6
• Molecular Formula: C47H73N11O16S
• Molecular Weight: 1080.21
• Mol file: 566173-30-6.mol

Synonyms:APP770 (586-595) (HUMAN, MOUSE, RAT);APP-IP;H-ILE-SER-TYR-GLY-ASN-ASP-ALA-LEU-MET-PRO-OH;AMYLOID BETA/A4 PROTEIN PRECURSOR770 (586-595) (HUMAN, MOUSE, RAT)

Chemical Property of AMYLOID BETA/A4 PROTEIN PRECURSOR770 (586-595) (HUMAN, MOUSE, RAT)

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Amyloid beta/A4 Protein Precursor770 (586-595) (human, mouse, rat) trifluoroacetate salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of AMYLOID BETA/A4 PROTEIN PRECURSOR770 (586-595) (HUMAN, MOUSE, RAT)

There total 1 articles about AMYLOID BETA/A4 PROTEIN PRECURSOR770 (586-595) (HUMAN, MOUSE, RAT) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(fluoren-9-ylmethoxycarbonyl)glycine (29022-11-5) + Fmoc-Leu-OH (35661-60-0) + N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine (35661-39-3,136132-75-7) + Fmoc-Pro-OH (71989-31-6) + Fmoc-Ile-OH (71989-23-6,251316-98-0) + N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-methionine (71989-28-1) → Ile-Ser-Tyr-Gly-Asn-Asp-Ala-Leu-Met-Pro (566173-30-6)

Guidance literature:

Fmoc-Pro-OH; With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 1h;

With piperidine; In N,N-dimethyl-formamide; for 0.333333h;

N-(fluoren-9-ylmethoxycarbonyl)glycine; Fmoc-Leu-OH; N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; Fmoc-Ile-OH; N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-methionine; Fmoc-Asn(pg)-OH; Fmoc-Asp(pg)-OH; Fmoc-Tyr(pg)-OH; Fmoc-Ser(pg)-OH; Further stages;

DOI:10.1002/anie.202108125

upstream raw materials:

N-(fluoren-9-ylmethoxycarbonyl)glycine

Fmoc-Leu-OH

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Fmoc-Pro-OH

Refernces