PYRIMIDINE-2-CARBOXYLIC ACID SODIUM

Base Information

• Chemical Name: PYRIMIDINE-2-CARBOXYLIC ACID SODIUM
• CAS No.: 562101-38-6
• Molecular Formula: C5H3N2NaO2
• Molecular Weight: 146.081
• Hs Code.: 2933599090
• Mol file: 562101-38-6.mol

Synonyms:PYRIMIDINE-2-CARBOXYLIC ACID SODIUM

Chemical Property of PYRIMIDINE-2-CARBOXYLIC ACID SODIUM

Chemical Property:

• PSA: 65.91000
• LogP: -1.15990

Purity/Quality:

NLT 98% ^*data from raw suppliers

sodiumpyrimidine-2-carboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PYRIMIDINE-2-CARBOXYLIC ACID SODIUM

There total 1 articles about PYRIMIDINE-2-CARBOXYLIC ACID SODIUM which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-cyanopyrimidine (14080-23-0) → sodium pyrimidine-2-carboxylate (562101-38-6)

Guidance literature:

With sodium hydroxide; In water; at 2 - 55 ℃; for 2h;

Reference yield: 5.0%

sodium pyrimidine-2-carboxylate (562101-38-6) + 2-aminoacetophenone (551-93-9) → N-(2-acetylphenyl)pyrimidine-2-carboxamide

Guidance literature:

With N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In dichloromethane; N,N-dimethyl-formamide; at 21 - 29 ℃; for 18h;

DOI:10.1016/j.ejmech.2016.08.046

Reference yield:

sodium pyrimidine-2-carboxylate (562101-38-6) + thiophenol (108-98-5) → S-phenyl pyrimidine-2-carbothioate (562101-41-1)

Guidance literature:

sodium pyrimidine-2-carboxylate; With Imidazole hydrochloride; 1,1'-carbonyldiimidazole; In acetonitrile; at 52 ℃; for 1h;

thiophenol; In acetonitrile; at 7 - 17 ℃; for 0.166667h;

upstream raw materials:

2-cyanopyrimidine

Downstream raw materials:

N-methoxy-N-methylpyrimidine-2-carboxamide

S-phenyl pyrimidine-2-carbothioate

Refernces