1-(6-Fluoropyridin-2-yl)ethanone

Base Information

Chemical Name:1-(6-Fluoropyridin-2-yl)ethanone
CAS No.:501009-05-8
Molecular Formula:C7H6FNO
Molecular Weight:139.1270432
Hs Code.:
European Community (EC) Number:878-771-5
NSC Number:190682
DSSTox Substance ID:DTXSID10307310
Wikidata:Q82054684
Mol file:501009-05-8.mol

Synonyms:1-(6-fluoropyridin-2-yl)ethanone;501009-05-8;ETHANONE,1-(6-FLUORO-2-PYRIDINYL)-;1-(6-FLUOROPYRIDIN-2-YL)ETHAN-1-ONE;1-(6-Fluoro-2-pyridinyl)ethanone;NSC190682;SCHEMBL2632248;DTXSID10307310;FUQLSKITBLFONX-UHFFFAOYSA-N;MFCD09263901;AKOS006332386;AB50226;CS-W021247;NSC-190682;DS-15674;FT-0704500;EN300-322301;F30144;A871662;Z1198219245

Suppliers and Price of 1-(6-Fluoropyridin-2-yl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(6-Fluoropyridin-2-yl)ethanone 98%
1g
$ 386.00

Chemenu
1-(6-fluoropyridin-2-yl)ethan-1-one 98%
1g
$ 365.00

American Custom Chemicals Corporation
1-(6-FLUOROPYRIDIN-2-YL)ETHANONE 95.00%
5MG
$ 502.70

Alichem
1-(6-Fluoropyridin-2-yl)ethanone
250mg
$ 160.68

Alichem
1-(6-Fluoropyridin-2-yl)ethanone
1g
$ 386.10

AK Scientific
1-(6-Fluoropyridin-2-yl)ethanone
100mg
$ 181.00

Total 21 raw suppliers

Chemical Property of 1-(6-Fluoropyridin-2-yl)ethanone

Chemical Property:

Boiling Point:211.0±20.0 °C(Predicted)
PKA:0.08±0.10(Predicted)
PSA：29.96000
Density:1.175±0.06 g/cm3(Predicted)
LogP:1.42330
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:139.043341977
Heavy Atom Count:10
Complexity:138

Purity/Quality:

98% ^*data from raw suppliers

1-(6-Fluoropyridin-2-yl)ethanone 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=NC(=CC=C1)F

Technology Process of 1-(6-Fluoropyridin-2-yl)ethanone

There total 1 articles about 1-(6-Fluoropyridin-2-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 676343-47-8
6-fluoro-N-methoxy-N-methylpicolinamide

: 676-58-4
methylmagnesium chloride

: 501009-05-8
1-(6-fluoro-pyridin-2-yl)ethanone

Guidance literature:: 6-fluoro-N-methoxy-N-methylpicolinamide; methylmagnesium chloride; In tetrahydrofuran; at 0 ℃; for 0.5h;

With water; ammonium chloride; In tetrahydrofuran; at 20 ℃;

Reference yield: 94.0%

: 501009-05-8
1-(6-fluoro-pyridin-2-yl)ethanone

: 960001-33-6
1-(6-fluoro-pyridin-2-yl)ethanol

Guidance literature:: 1-(6-fluoro-pyridin-2-yl)ethanone; With diisobutylaluminium hydride; In tetrahydrofuran; cyclohexane; at -78 ℃; for 0.75h;

With water; Rochelle's salt; isopropyl alcohol; In tetrahydrofuran; cyclohexane; at 20 ℃; for 1.5h;

Reference yield:

: 501009-05-8
1-(6-fluoro-pyridin-2-yl)ethanone

: C₁₄H₁₃FN₂O

Guidance literature:: Multi-step reaction with 2 steps

1: Ru(OCOCH₃)2{(S)-2,2'-bis(diphenylphosphino)-1,1'-dinaphthyl)}; 2,2,2-trifluoroacetic acid ammonia; hydrogen / tetrahydrofuran / 90 °C / 6000.6 Torr / Autoclave

2: triethylamine

With Ru(OCOCH₃)2{(S)-2,2'-bis(diphenylphosphino)-1,1'-dinaphthyl)}; hydrogen; 2,2,2-trifluoroacetic acid ammonia; triethylamine; In tetrahydrofuran;
DOI:10.1021/acs.orglett.1c00848